A Randomized, Open-label, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 Years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, for Pre-exposure Prophylaxis of COVID-19
Public ClinicalTrials.gov record NCT05375760. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Randomized, Open-label, Multicenter, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 Years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, a Combination Product of Two Monoclonal Antibodies (Tixagevimab and Cilgavimab), for Pre-exposure Prophylaxis of COVID-19
Study identification
- NCT ID
- NCT05375760
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 251 participants
Conditions and interventions
Conditions
Interventions
- AZD7442 (tixagevimab [AZD8895] + cilgavimab [AZD1061]) Biological
Biological
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 8, 2022
- Primary completion
- Oct 3, 2023
- Completion
- Oct 3, 2023
- Last update posted
- Oct 22, 2024
2022 – 2023
United States locations
- U.S. sites
- 16
- U.S. states
- 8
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35215 | — |
| Research Site | Modesto | California | 95350 | — |
| Research Site | Westminster | California | 92683 | — |
| Research Site | Hollywood | Florida | 33024 | — |
| Research Site | Lake City | Florida | 32055 | — |
| Research Site | Miami | Florida | 33125 | — |
| Research Site | Miami Lakes | Florida | 33014 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Wesley Chapel | Florida | 33545 | — |
| Research Site | West Palm Beach | Florida | 33409 | — |
| Research Site | Chicago | Illinois | 60640 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Knoxville | Tennessee | 37920 | — |
| Research Site | Austin | Texas | 78745 | — |
| Research Site | El Paso | Texas | 79925 | — |
| Research Site | Annandale | Virginia | 22003 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05375760, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2024 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05375760 live on ClinicalTrials.gov.