A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder
Public ClinicalTrials.gov record NCT05376150. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Proof-of-Concept, Randomized, Double-blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 in Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, Phase 2, double-blind, randomized, parallel-arm, placebo-controlled clinical trial to evaluate the efficacy, safety, and tolerability of XEN1101 in subjects with Major Depressive Disorder.
Study identification
- NCT ID
- NCT05376150
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 168 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 19, 2022 (Actual)
- Primary completion
- Sep 18, 2023 (Actual)
- Completion
- Oct 16, 2023 (Actual)
- Last update posted
- Sep 21, 2026
2022 – 2023
United States locations
- U.S. sites
- 20
- U.S. states
- 9
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Research Center | Anaheim | California | 92805 | — |
| Sunwise Clinical Research, LLC | Lafayette | California | 94549 | — |
| California Neuropsychopharmacology Clinical Research Institute | Pico Rivera | California | 90660 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Meridian International Research | Miami | Florida | 33014 | — |
| Global Medical Institutes (GMI) | Miami | Florida | 33125 | — |
| CCM Clinical Reseach Group, LLC | Miami | Florida | 33133 | — |
| i-Research, Atlanta | Decatur | Georgia | 30030 | — |
| Psych Atlanta, PC | Marietta | Georgia | 30060 | — |
| iResearch | Savannah | Georgia | 31405 | — |
| Revive Research Institute, Inc. | Elgin | Illinois | 60123 | — |
| Altea Research | Las Vegas | Nevada | 89102 | — |
| Hassman Research Institute | Marlton | New Jersey | 08009 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Neurobehavioral Research, Inc. (NBR) | Cedarhurst | New York | 11516 | — |
| Manhattan Behavioral Medicine, PLLC | New York | New York | 10036 | — |
| Richard M Weisler and Association | Raleigh | North Carolina | 27609 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| AIM Trials | Plano | Texas | 75093 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05376150, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05376150 live on ClinicalTrials.gov.