Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
Public ClinicalTrials.gov record NCT05377489. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single-arm, Open-label, Phase III Trial to Evaluate the Safety and Tolerability of Intra-articular Injections of RTX-GRT7039 in Subjects With Moderate to Severe Pain Associated With Osteoarthritis of the Knee.
Study identification
- NCT ID
- NCT05377489
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Grünenthal GmbH
- Industry
- Enrollment
- 714 participants
Conditions and interventions
Conditions
Interventions
- RTX-GRT7039 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 14, 2022
- Primary completion
- May 14, 2025
- Completion
- May 14, 2025
- Last update posted
- Mar 11, 2026
2022 – 2025
United States locations
- U.S. sites
- 27
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis and Rheumatology Associates (AARA) P.C | Glendale | Arizona | 85306 | — |
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| Acclaim Clinical Research, Inc. | San Diego | California | 92120 | — |
| Westlake Medical Research | Thousand Oaks | California | 91360 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Gulfcoast Research Institute | Sarasota | Florida | 34232 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Injury Care Research | Boise | Idaho | 83713 | — |
| Chicago Clinical Research Institute Inc. | Chicago | Illinois | 60607 | — |
| OrthoIndy, Inc. | Greenwood | Indiana | 46143 | — |
| University Of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Neuroscience Research Center, LLC | Overland Park | Kansas | 66210 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01605 | — |
| Oakland Medical Research Center | Troy | Michigan | 48085 | — |
| Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| Las Vegas Clinical Trials, LLC | North Las Vegas | Nevada | 89030 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| M3-Emerging Medical Research, LLC | Durham | North Carolina | 27704 | — |
| M3-Emerging Medical Research, LLC | Raleigh | North Carolina | 27704 | — |
| University Orthopedics Center | State College | Pennsylvania | 16801 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Accellacare-Knoxville | Knoxville | Tennessee | 37912 | — |
| Tekton Research, Inc. | San Antonio | Texas | 78229 | — |
| Wasatch Clinical Research | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05377489, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05377489 live on ClinicalTrials.gov.