Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD)
Public ClinicalTrials.gov record NCT05381948. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Prospective, Randomized, Double-Masked, Parallel Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept in Subjects With Wet AMD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 2 randomized, double -masked study comparing the efficacy of EYP-1901 at 2 dose levels: 2060 microgram (mcg) and 3090 mcg against aflibercept.
Study identification
- NCT ID
- NCT05381948
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 161 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2022 (Actual)
- Primary completion
- Nov 29, 2023 (Actual)
- Completion
- Apr 24, 2024 (Actual)
- Last update posted
- Oct 15, 2025
2022 – 2024
United States locations
- U.S. sites
- 67
- U.S. states
- 25
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| EyePoint Investigative Site | Phoenix | Arizona | 85053 | — |
| EyePoint Investigative Site | Springdale | Arkansas | 72762 | — |
| EyePoint Investigative Site | Beverly Hills | California | 90211 | — |
| EyePoint Investigative Site | Campbell | California | 95008 | — |
| EyePoint Investigative Site | Encino | California | 91436 | — |
| EyePoint Investigative Site | Fullerton | California | 92835 | — |
| EyePoint Investigative Site | Glendale | California | 91203 | — |
| EyePoint Investigative Site | Huntington Beach | California | 92647 | — |
| EyePoint Investigative Site | Irvine | California | 92697 | — |
| EyePoint Investigative Site | Pasadena | California | 91107 | — |
| EyePoint Investigative Site | Poway | California | 92064 | — |
| EyePoint Investigative Site | Redlands | California | 92373 | — |
| EyePoint Investigative Site | Sacramento | California | 95825 | — |
| EyePoint Investigative Site | Walnut Creek | California | 94598 | — |
| EyePoint Investigative Site | Lakewood | Colorado | 80228 | — |
| EyePoint Investigative Site | Clearwater | Florida | 33761 | — |
| EyePoint Investigative Site | Coral Springs | Florida | 33067 | — |
| EyePoint Investigative Site | Lakeland | Florida | 33805 | — |
| EyePoint Investigative Site | Melbourne | Florida | 32901 | — |
| EyePoint Investigative Site | Miami | Florida | 33143 | — |
| EyePoint Investigative Site | Pensacola | Florida | 32503 | — |
| EyePoint Investigative Site | Sarasota | Florida | 34239 | — |
| EyePoint Investigative Site | St. Petersburg | Florida | 33711 | — |
| EyePoint Investigative Site | Tampa | Florida | 33609 | — |
| EyePoint Investigative Site | Winter Haven | Florida | 33880 | — |
| EyePoint Investigative Site | Marietta | Georgia | 30060 | — |
| EyePoint Investigative Site | ‘Aiea | Hawaii | 96701 | — |
| EyePoint Investigative Site | Chicago | Illinois | 60616 | — |
| EyePoint Investigative Site | Lemont | Illinois | 60439 | — |
| EyePoint Investigative Site | Carmel | Indiana | 46290 | — |
| EyePoint Investigative Site | West Des Moines | Iowa | 50266 | — |
| EyePoint Investigative Site | Baltimore | Maryland | 21209 | — |
| EyePoint Investigative Site | Hagerstown | Maryland | 21740 | — |
| EyePoint Investigative Site | Owings Mills | Maryland | 21117 | — |
| EyePoint Investigative Site | Boston | Massachusetts | 02114 | — |
| EyePoint Investigative Site | Springfield | Massachusetts | 01107 | — |
| EyePoint Investigative Site | Grand Rapids | Michigan | 49446 | — |
| EyePoint Investigative Site | Saint Louis | Michigan | 55416 | — |
| EyePoint Investigative Site | St Louis | Missouri | 63128 | — |
| EyePoint Investigative Site | Reno | Nevada | 89502 | — |
| EyePoint Investigative Site | Teaneck | New Jersey | 07666 | — |
| EyePoint Investigative Site | Great Neck | New York | 11021 | — |
| EyePoint Investigative Site | Hauppauge | New York | 11788 | — |
| EyePoint Investigative Site | Liverpool | New York | 13088 | — |
| EyePoint Investigative Site | Shirley | New York | 11967 | — |
| EyePoint Investigative Site | Asheville | North Carolina | 28803 | — |
| EyePoint Investigative Site | Wake Forest | North Carolina | 27587 | — |
| EyePoint Investigative Site | Eugene | Oregon | 97401 | — |
| EyePoint Investigative Site | Portland | Oregon | 97239 | — |
| EyePoint Investigative Site | Springfield | Oregon | 97488 | — |
| EyePoint Investigative Site | Charleston | South Carolina | 29414 | — |
| EyePoint Investigative Site | West Columbia | South Carolina | 29169 | — |
| EyePoint Investigative Site | Germantown | Tennessee | 38138 | — |
| EyePoint Investigative Site | Nashville | Tennessee | 37203 | — |
| EyePoint Investigative Site | Abilene | Texas | 79606 | — |
| EyePoint Investigative Sites | Austin | Texas | 78750 | — |
| EyePoint Investigative Site | Dallas | Texas | 75231 | — |
| EyePoint Investigative Sites | Houston | Texas | 77025 | — |
| EyePoint Investigative Site | McAllen | Texas | 78503 | — |
| EyePoint Investigative Site | Plano | Texas | 75075 | — |
| EyePoint Investigative Site | San Antonio | Texas | 78240 | — |
| EyePoint Investigative Site | The Woodlands | Texas | 77384 | — |
| EyePoint Investigative Site | Salt Lake City | Utah | 84107 | — |
| EyePoint Investigative Site | Fairfax | Virginia | 22031 | — |
| EyePoint Investigative Site | Lynchburg | Virginia | 24502 | — |
| EyePoint Investigative Site | Warrenton | Virginia | 20186 | — |
| EyePoint Investigative Site | Silverdale | Washington | 98383 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05381948, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2025 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05381948 live on ClinicalTrials.gov.