Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis
Public ClinicalTrials.gov record NCT05384249. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Pivotal Study to Evaluate the Efficacy and Safety of Izokibep in Subjects with Non-infectious, Intermediate-, Posterior- or Pan-uveitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin-17A, to which it binds with high affinity. This study investigates izokibep in subjects with active non-infectious, intermediate-, posterior- or pan-uveitis requiring high-dose steroids.
Study identification
- NCT ID
- NCT05384249
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 96 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 23, 2022 (Actual)
- Primary completion
- Feb 7, 2025 (Actual)
- Completion
- Feb 7, 2025 (Actual)
- Last update posted
- Feb 21, 2025
2022 – 2025
United States locations
- U.S. sites
- 36
- U.S. states
- 21
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site | Phoenix | Arizona | 85020-5505 | — |
| Clinical Research Site | Bakersfield | California | 93309 | — |
| Clinical Research Site | Beverly Hills | California | 90211-1841 | — |
| Clinical Research Site | Los Angeles | California | 90033-1036 | — |
| Clinical Research Site | Los Angeles | California | 90095-7065 | — |
| Clinical Research Site | Palo Alto | California | 94303 | — |
| Clinical Research Site | Pasadena | California | 91107-3747 | — |
| Clinical Research Site | Redlands | California | 92373 | — |
| Clinical Research Site | Sacramento | California | 95825 | — |
| Clinical Research Site | San Francisco | California | 94109 | — |
| Clinical Research Site | Denver | Colorado | 80246 | — |
| Clinical Research Site | Clearwater | Florida | 33761 | — |
| Clinical Research Site | Marietta | Georgia | 30060-8935 | — |
| Clinical Research Site | Oak Park | Illinois | 60304-1096 | — |
| Clinical Research Site | Indianapolis | Indiana | 46290 | — |
| Clinical Research Site | Hagerstown | Maryland | 21740-5940 | — |
| Clinical Research Site | Waltham | Massachusetts | 02451 | — |
| Clinical Research Site | Detroit | Michigan | 48201-1423 | — |
| Clinical Research Site | Palisades Park | New Jersey | 07650-2322 | — |
| Clinical Research Site | New York | New York | 10003 | — |
| Clinical Research Site | Winston-Salem | North Carolina | 27157 | — |
| Clinical Research Site | Cleveland | Ohio | 44106 | — |
| Clinical Research Site | Cleveland | Ohio | 44195-0001 | — |
| Clinical Research Site | Portland | Oregon | 97239 | — |
| Clinical Research Site | Erie | Pennsylvania | 16507-1429 | — |
| Clinical Research Site | Pittsburgh | Pennsylvania | 15213 | — |
| Clinical Research Site | Charleston | South Carolina | 29414 | — |
| Clinical Research Site | Nashville | Tennessee | 37232 | — |
| Clinical Research Site | Austin | Texas | 78714 | — |
| Clinical Research Site | Bellaire | Texas | 77401-3218 | — |
| Clinical Research Site | Houston | Texas | 77025-1756 | — |
| Clinical Research Site | Houston | Texas | 77030 | — |
| Clinical Research Site | Houston | Texas | 77494-3286 | — |
| Clinical Research Site | Plano | Texas | 75075-5025 | — |
| Clinical Research Site | Spokane | Washington | 99204-2509 | — |
| Clinical Research Site | Madison | Wisconsin | 53705-3644 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05384249, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 21, 2025 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05384249 live on ClinicalTrials.gov.