ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)
Public ClinicalTrials.gov record NCT05388708. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
ASCEND researchers are partnering with families of children who receive extracorporeal membrane oxygenation (ECMO) after a sudden failure of breathing named pediatric acute respiratory distress syndrome (PARDS). ECMO is a life support technology that uses an artificial lung outside of the body to do the lung's work. ASCEND has two objectives. The first objective is to learn more about children's abilities and quality of life among ECMO-supported children in the year after they leave the pediatric intensive care unit. The second objective is to compare short and long-term patient outcomes in two groups of children: one group managed with a mechanical ventilation protocol that reserves the use of extracorporeal membrane oxygenation (ECMO) until protocol failure to another group supported on ECMO per usual care.
Study identification
- NCT ID
- NCT05388708
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 550 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 14 Days to 20 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 4, 2021 (Actual)
- Primary completion
- Jun 30, 2027 (Estimated)
- Completion
- Sep 30, 2027 (Estimated)
- Last update posted
- Jul 14, 2026
2021 – 2027
United States locations
- U.S. sites
- 72
- U.S. states
- 37
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's of Alabama | Birmingham | Alabama | 35233 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| Loma Linda University Children's Hospital | Loma Linda | California | 92354 | — |
| UCLA Mattel Children's Hospital | Los Angeles | California | 90095 | — |
| Valley Children's Hospital | Madera | California | 93636 | — |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Lucile Packard Children's Hospital Stanford | Palo Alto | California | 94304 | — |
| UCSF Benioff Children's Hospital - San Francisco | San Francisco | California | 94158 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Connecticut Children's Medical Center | Hartford | Connecticut | 06106 | — |
| Yale New Haven Children's Hospital | New Haven | Connecticut | 06511 | — |
| Nemours Children's Hospital, Delaware | Wilmington | Delaware | 19803 | — |
| UF Health Shands Children's Hospital | Gainesville | Florida | 32608 | — |
| Orlando Health Arnold Palmer Hospital for Children | Orlando | Florida | 32806 | — |
| Nemours Children's Hospital, Florida | Orlando | Florida | 32827 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30342 | — |
| Kapi'olani Medical Center for Women & Children | Honolulu | Hawaii | 96826 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| Comer Children's Hospital | Chicago | Illinois | 60637 | — |
| OSF Healthcare Children's Hospital of Illinois | Peoria | Illinois | 61637 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| University of Iowa Health Care Stead Family Children's Hospital | Iowa City | Iowa | 52242 | — |
| Norton Children's Hospital | Louisville | Kentucky | 40202 | — |
| Ochsner LSU Health Shreveport | Shreveport | Louisiana | 71103 | — |
| Johns Hopkins Children's Center | Baltimore | Maryland | 21287 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan - Mott Children's Hospital | Ann Arbor | Michigan | 48109 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Children's Minnesota Hospital | Minneapolis | Minnesota | 55404 | — |
| Mayo Eugenio Litta Children's Hospital | Rochester | Minnesota | 55902 | — |
| Children's Mercy | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| St. Louis Children's Hospital | St Louis | Missouri | 63110 | — |
| Children's Nebraska | Omaha | Nebraska | 68114 | — |
| UNM Children's Hospital | Albuquerque | New Mexico | 87106 | — |
| John R. Oishei Children's Hospital | Buffalo | New York | 14203 | — |
| Hassenfeld Children's Hospital at NYU Langone | New York | New York | 10016 | — |
| NewYork-Presbyterian Morgan Stanley Children's Hospital | New York | New York | 10032 | — |
| NewYork-Presbyterian Komansky Children's Hospital | New York | New York | 10065 | — |
| Cohen Children's Medical Center | Queens | New York | 11040 | — |
| N.C. Children's Hospital | Chapel Hill | North Carolina | 27514 | — |
| Duke Children's Hospital & Health Center | Durham | North Carolina | 27705 | — |
| Atrium Health Wake Forest Baptist | Brenner Children's Hospital | Winston-Salem | North Carolina | 27157 | — |
| Akron Children's Hospital | Akron | Ohio | 44308 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Cleveland Clinic Children's Hospital | Cleveland | Ohio | 44106 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43215 | — |
| Oklahoma Children's Hospital OU Health | Oklahoma City | Oklahoma | 73104 | — |
| OHSU Doernbecher Children's Hospital | Portland | Oregon | 97239 | — |
| Penn State Health Children's Hospital | Hershey | Pennsylvania | 17033 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Hasbro Children's | Providence | Rhode Island | 02903 | — |
| MUSC Shawn Jenkins Children's Hospital | Charleston | South Carolina | 29425 | — |
| Sanford Children's Hospital | Sious Falls | South Dakota | 57105 | — |
| Le Bonheur Children's Hospital | Memphis | Tennessee | 38103 | — |
| Monroe Carell Jr. Children's Hospital at Vanderbilt | Nashville | Tennessee | 37232 | — |
| Dell Children's Medical Center | Austin | Texas | 78723 | — |
| Medical City Children's Hospital | Dallas | Texas | 75230 | — |
| Children's Medical Center Dallas | Dallas | Texas | 75235 | — |
| Children's Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| University Health Women's & Children's Hospital | San Antonio | Texas | 78229 | — |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | — |
| UVA Children's Hospital | Charlottesville | Virginia | 22903 | — |
| Inova L.J. Murphy Children's Hospital | Falls Church | Virginia | 22042 | — |
| Seattle Children's Hospital | Seattle | Washington | 98105 | — |
| UW Health American Family Children's Hospital | Madison | Wisconsin | 53792 | — |
| Children's Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05388708, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 14, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05388708 live on ClinicalTrials.gov.