A Study of Modified mRNA Vaccines in Healthy Adults
Public ClinicalTrials.gov record NCT05397223. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Modified mRNA Vaccines Using a Systems Biology Approach in Healthy Adults
Study identification
- NCT ID
- NCT05397223
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- ModernaTX, Inc.
- Industry
- Enrollment
- 308 participants
Conditions and interventions
Interventions
- FLUAD® Biological
- mRNA-1010 Biological
- mRNA-1273 Biological
- mRNA-1345 Biological
- mRNA-1647 Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 23, 2022
- Primary completion
- Feb 26, 2026
- Completion
- Feb 26, 2026
- Last update posted
- Mar 11, 2026
2022 – 2026
United States locations
- U.S. sites
- 8
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CenExel | Hollywood | Florida | 33024 | — |
| Meridian Clinical Research | Savannah | Georgia | 31406 | — |
| Meridian Clinical Research | Sioux City | Iowa | 51106 | — |
| Johnson County Clinical Trials | Lenexa | Kansas | 66219 | — |
| Meridian Clinical Research | Lincoln | Nebraska | 68510 | — |
| Benchmark Research | Austin | Texas | 78705 | — |
| Tekton Research, Inc | Austin | Texas | 78745 | — |
| DM Clinical Research- Texas Center for Drug Development | Houston | Texas | 77081 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05397223, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05397223 live on ClinicalTrials.gov.