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Completed Phase 1 Interventional Accepts healthy volunteers

A Study of Modified mRNA Vaccines in Healthy Adults

ClinicalTrials.gov ID: NCT05397223

Public ClinicalTrials.gov record NCT05397223. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 4:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Modified mRNA Vaccines Using a Systems Biology Approach in Healthy Adults

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.

Study identification

NCT ID
NCT05397223
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
ModernaTX, Inc.
Industry
Enrollment
308 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 24, 2022 (Actual)
Primary completion
Feb 27, 2026 (Actual)
Completion
Feb 27, 2026 (Actual)
Last update posted
Mar 12, 2026

2022 – 2026

United States locations

U.S. sites
8
U.S. states
6
U.S. cities
7
Facility City State ZIP Site status
CenExel Hollywood Florida 33024 —
Meridian Clinical Research Savannah Georgia 31406 —
Meridian Clinical Research Sioux City Iowa 51106 —
Johnson County Clinical Trials Lenexa Kansas 66219 —
Meridian Clinical Research Lincoln Nebraska 68510 —
Benchmark Research Austin Texas 78705 —
Tekton Research, Inc Austin Texas 78745 —
DM Clinical Research- Texas Center for Drug Development Houston Texas 77081 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05397223, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 12, 2026 · Synced Oct 18, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05397223 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →