A Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE)
Public ClinicalTrials.gov record NCT05398445. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, 24-week, Randomized, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety and Tolerability of Rocatinlimab (AMG 451) Monotherapy in Adult Subjects With Moderate-to-severe Atopic Dermatitis (AD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of rocatinlimab in monotherapy treatment.
Study identification
- NCT ID
- NCT05398445
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 769 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2022 (Actual)
- Primary completion
- Nov 28, 2024 (Actual)
- Completion
- Jan 13, 2025 (Actual)
- Last update posted
- Jul 23, 2026
2022 – 2025
United States locations
- U.S. sites
- 50
- U.S. states
- 25
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Dermatology and Skin Health Center | Birmingham | Alabama | 35244 | — |
| Alliance Dermatology and Mohs Center | Phoenix | Arizona | 85032 | — |
| Anaheim Clinical Trials | Anaheim | California | 92801 | — |
| First OC Dermatology | Fountain Valley | California | 92708 | — |
| Kaiser Permanente - Glendale Medical Center | Glendale | California | 91203 | — |
| Long Beach Research Institute | Long Beach | California | 90805 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| Cura Clinical Research | Sherman Oaks | California | 91403 | — |
| IMMUNOe Research Centers | Centennial | Colorado | 80112 | — |
| Skin Care Research Incorporated | Boca Raton | Florida | 33486 | — |
| Palm Beach Dermatology Group | Delray Beach | Florida | 33484 | — |
| Global Research Associates | Homestead | Florida | 33030 | — |
| Healthy Life Research | Miami | Florida | 33175 | — |
| Savin Medical Group LLC | Miami Lakes | Florida | 33014 | — |
| Kirsch Dermatology LLC | Naples | Florida | 34102 | — |
| Pure Skin Dermatology and Aesthetics | Orlando | Florida | 32819 | — |
| Industrial Medicine Associates Ima Clinical Research Inc | St. Petersburg | Florida | 33709 | — |
| Genesis Clinical Research LLC | Tampa | Florida | 33606 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| DeNova Research | Chicago | Illinois | 60611 | — |
| Dundee Dermatology | West Dundee | Illinois | 60118 | — |
| The Indiana Clinical Trials Center PC | Plainfield | Indiana | 46168 | — |
| Institute for Asthma and Allergy | Chevy Chase | Maryland | 20815 | — |
| Continental Clinical Solutions, LLC | Towson | Maryland | 21204 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Onyx Clinical Research | Flint | Michigan | 48532 | — |
| Dermatology and Skin Cancer Center of Lees Summit | Lee's Summit | Missouri | 64064 | — |
| Jubilee Clinical Research Inc | Las Vegas | Nevada | 89106 | — |
| Allcutis Research, Llc - Portsmouth | Portsmouth | New Hampshire | 03801 | — |
| Continental Clinical Solutions - Cherry Hill | Cherry Hill | New Jersey | 08034 | — |
| Industrial Medicine Associates Ima Clinical Research Inc | Hartsdale | New York | 10530 | — |
| Sadick Research Group | New York | New York | 10075 | — |
| Dermatology Specialists of Charlotte | Charlotte | North Carolina | 28277 | — |
| Onsite Clinical Solutions | Charlotte | North Carolina | 28277 | — |
| Wilmington Dermatology Center | Wilmington | North Carolina | 28405 | — |
| The Skin Surgery Center for Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| Optima Research | Boardman | Ohio | 44512 | — |
| ClinOhio Research Services | Columbus | Ohio | 43213 | — |
| Unity Clinical Research | Oklahoma City | Oklahoma | 73118 | — |
| Dermatology Research Center of Oklahoma, PLLC | Tulsa | Oklahoma | 74132 | — |
| Essential Medical Research LLC | Tulsa | Oklahoma | 74137 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| DermDox Dermatology, LLC | Sugarloaf | Pennsylvania | 18249 | — |
| Cumberland Skin Center | Hermitage | Tennessee | 37076 | — |
| Dermatology Treatment and Research Center PA | Dallas | Texas | 75230 | — |
| The Woodlands Dermatology Associates | The Woodlands | Texas | 77380 | — |
| Education and Research Foundation Inc | Lynchburg | Virginia | 24501 | — |
| Frontier Derm Partners | Mill Creek | Washington | 98012 | — |
| West Virginia Research Institute | Morgantown | West Virginia | 26505 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 152 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05398445, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 23, 2026 · Synced Oct 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05398445 live on ClinicalTrials.gov.