A Study to Evaluate the Efficacy and Safety of Rencofilstat in Subjects With NASH and Advanced Liver Fibrosis
Public ClinicalTrials.gov record NCT05402371. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2B, Randomized, Multi-Center, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rencofilstat in Adult Subjects With Nonalcoholic Steatohepatitis and Advanced Liver Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, placebo-controlled, parallel-dosing, multi-center study to evaluate the efficacy and safety of Rencofilstat as evidenced by histopathological improvements in fibrosis in adult NASH subjects with F2 or F3 fibrosis (NASH CRN system). Antifibrotic biomarker activity will be evaluated on an exploratory basis.
Study identification
- NCT ID
- NCT05402371
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 120 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 15, 2022 (Actual)
- Primary completion
- May 2025 (Estimated)
- Completion
- Sep 2025 (Estimated)
- Last update posted
- May 3, 2024
2022 – 2025
United States locations
- U.S. sites
- 39
- U.S. states
- 13
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Affiliated Research Center | Huntsville | Alabama | 35801 | — |
| Arizona Liver Health-Chandler | Chandler | Arizona | 85224 | — |
| Arizona Liver Health | Peoria | Arizona | 85381 | — |
| Adobe Clinical Research, LLC | Tucson | Arizona | 85712 | — |
| Arizona Liver Health-Tuscon | Tucson | Arizona | 85712 | — |
| Preferred Research Partners, Inc. | Little Rock | Arkansas | 72211 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72117 | — |
| National Research Institute | Huntington Park | California | 90255 | — |
| National Research Institute | Los Angeles | California | 90057 | — |
| National Research Institute | Panorama City | California | 91402 | — |
| National Research Institute | Santa Ana | California | 92704 | — |
| Synergy Healthcare, LLC | Bradenton | Florida | 34208 | — |
| Tampa Bay Medical Research, Inc. | Clearwater | Florida | 33761 | — |
| Top Medical Research, Inc. | Cutler Bay | Florida | 33189 | — |
| Integrity Clinical Research, LLC | Doral | Florida | 33166 | — |
| Evolution Clinical Trials, Inc. | Hialeah Gardens | Florida | 33016 | — |
| Borland Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| Ocala GI Research | Lady Lake | Florida | 32159 | — |
| Accel Research Sites-Lakeland CRU | Lakeland | Florida | 33803 | — |
| Future Care Solutions, LLC | Miami | Florida | 33165 | — |
| Entrust Clinical Research | Miami | Florida | 33176 | — |
| United Reseach Group | Miami | Florida | 33186 | — |
| Omega Research Consultants, LLC | Orlando | Florida | 32810 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Covenant Research and Clinics | Sarasota | Florida | 34240 | — |
| Southeast Clinical Research Center | Dalton | Georgia | 30720 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Digestive Research Alliance of Michiana, LLC | South Bend | Indiana | 46635 | — |
| Delta Research Partners | Bastrop | Louisiana | 71220 | — |
| Mid-Atlantic GI Research, LLC | Greenbelt | Maryland | 20770 | — |
| AIG Digestive Disease Research, LLC | Florham Park | New Jersey | 07932 | — |
| Pinnacle Clinical Research-Austin | Austin | Texas | 78757 | — |
| South Texas Research Institute | Brownsville | Texas | 78520 | — |
| South Texas Research Institute | Edinburg | Texas | 78539 | — |
| LinQ Research, LLC | Pearland | Texas | 77584 | — |
| Pinnacle Clinical Research-San Antonio | San Antonio | Texas | 78229 | — |
| Bon Secours Liver Institute of Hampton Roads | Newport News | Virginia | 23602 | — |
| GI Select Health Research, LLC | Richmond | Virginia | 23236 | — |
| Velocity Clinical Spokane | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05402371, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2024 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05402371 live on ClinicalTrials.gov.