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Completed Phase 1 Interventional Results available

A Study of Elpipodect (MK-8189) in Participants With Schizophrenia (MK-8189-014)

ClinicalTrials.gov ID: NCT05406440

Public ClinicalTrials.gov record NCT05406440. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 8:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multiple Ascending Dose Clinical Study to Evaluate the Safety, Tolerability, PK and the Effect of MK-8189 on QTc in Participants With Schizophrenia

Study identification

NCT ID
NCT05406440
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
53 participants

Conditions and interventions

Conditions

Interventions

  • Elpipodect Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 11, 2022
Primary completion
Feb 23, 2023
Completion
Feb 23, 2023
Last update posted
Apr 28, 2026

2022 – 2023

United States locations

U.S. sites
3
U.S. states
2
U.S. cities
3
Facility City State ZIP Site status
Collaborative Neuroscience Research, LLC ( Site 0004) Garden Grove California 92845
California Clinical Trials Medical Group managed by PAREXEL ( Site 0002) Glendale California 91206
Hassman Research Institute Marlton Site ( Site 0003) Marlton New Jersey 08053

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05406440, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 28, 2026 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05406440 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →