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Active, not recruiting Phase 2 Interventional

Novel α2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial

ClinicalTrials.gov ID: NCT05408546

Public ClinicalTrials.gov record NCT05408546. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 3:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of the Safety and Thrombolytic Effects of Ascending Doses of TS23 in Subjects With Intermediate-Risk (Sub-Massive) Acute Pulmonary Embolism

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Phase II trial of TS23

Study identification

NCT ID
NCT05408546
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Translational Sciences, Inc.
Industry
Enrollment
64 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 24, 2023 (Actual)
Primary completion
Aug 31, 2026 (Estimated)
Completion
Nov 2026 (Estimated)
Last update posted
Jul 1, 2026

2023 – 2026

United States locations

U.S. sites
13
U.S. states
10
U.S. cities
12
Facility City State ZIP Site status
Banner University Medical Center Phoenix Arizona 85004 —
Banner University Medical Center - Tucson Tucson Arizona 85004 —
Cedars Sinai Medical Center Los Angeles California 90048 —
Cottage Hospital Santa Barbara California 93105 —
Wellstar MCG Health Medical Center Augusta Georgia 30912 —
Lifebridge Health Baltimore Maryland 21215 —
Tuft University Hospital Boston Massachusetts 02116 —
Henry Ford Hospital Detroit Michigan 48207 —
Wake Forest University/Atrium Health's Carolinas Medical Center Winston-Salem North Carolina 27103 —
Fairview Hospital Cleveland Ohio 44111 —
Cleveland Clinic Cleveland Ohio 44195 —
Temple University Hospital Philadelphia Pennsylvania 19140 —
Texas Tech University Health Sciences Center at El Paso El Paso Texas 79430 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05408546, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 1, 2026 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05408546 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →