Novel α2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial
Public ClinicalTrials.gov record NCT05408546. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of the Safety and Thrombolytic Effects of Ascending Doses of TS23 in Subjects With Intermediate-Risk (Sub-Massive) Acute Pulmonary Embolism
Study identification
- NCT ID
- NCT05408546
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Translational Sciences, Inc.
- Industry
- Enrollment
- 64 participants
Conditions and interventions
Conditions
Interventions
- TS23 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 23, 2023
- Primary completion
- Aug 30, 2026
- Completion
- Oct 31, 2026
- Last update posted
- Jun 30, 2026
2023 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 10
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University Medical Center | Phoenix | Arizona | 85004 | — |
| Banner University Medical Center - Tucson | Tucson | Arizona | 85004 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Cottage Hospital | Santa Barbara | California | 93105 | — |
| Wellstar MCG Health Medical Center | Augusta | Georgia | 30912 | — |
| Lifebridge Health | Baltimore | Maryland | 21215 | — |
| Tuft University Hospital | Boston | Massachusetts | 02116 | — |
| Henry Ford Hospital | Detroit | Michigan | 48207 | — |
| Wake Forest University/Atrium Health's Carolinas Medical Center | Winston-Salem | North Carolina | 27103 | — |
| Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Texas Tech University Health Sciences Center at El Paso | El Paso | Texas | 79430 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05408546, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 30, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05408546 live on ClinicalTrials.gov.