Effectiveness of CRD-740 in Heart Failure
Public ClinicalTrials.gov record NCT05409183. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Assess the Effectiveness of CRD-740 in Subjects With Chronic Heart Failure (CARDINAL-HF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study evaluating the effectiveness of CRD-740 in patients with either Heart Failure with Reduced Ejection Fraction (HFrEF) or Heart Failure with Preserved Ejection Fraction (HFpEF) after 12 weeks of treatment. The primary objective in Part A is to assess the effect of CRD-740 compared to placebo in plasma cGMP at Week 4 in HFrEF. Part B of the study was not conducted in favor of redesigned new studies.
Study identification
- NCT ID
- NCT05409183
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 26, 2022 (Actual)
- Primary completion
- May 2, 2023 (Actual)
- Completion
- Jul 25, 2023 (Actual)
- Last update posted
- Dec 19, 2024
2022 – 2023
United States locations
- U.S. sites
- 17
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardurion Investigative Site | Alexander City | Alabama | 35010 | — |
| Cardurion Investigative Site | Birmingham | Alabama | 35211 | — |
| Cardurion Investigative Site | Fairhope | Alabama | 36532 | — |
| Cardurion Investigative Site | Torrance | California | 90502 | — |
| Cardurion Investigative Site | Hialeah | Florida | 33016 | — |
| Cardurion Investigative Site | Miami | Florida | 33133 | — |
| Cardurion Investigative Site | Miami | Florida | 33169 | — |
| Cardurion Investigative Site | Naples | Florida | 34102 | — |
| Cardurion Investigative Site | Tampa | Florida | 33612 | — |
| Cardurion Investigative Site | Atlanta | Georgia | 30303 | — |
| Cardurion Investigative Site | Hazel Crest | Illinois | 60429 | — |
| Cardurion Investigative Site | Alexandria | Louisiana | 71301 | — |
| Cardurion Investigative Site | Minneapolis | Minnesota | 55415 | — |
| Cardurion Investigative Site | Greensboro | North Carolina | 27408 | — |
| Cardurion Investigative Site | Tullahoma | Tennessee | 37388 | — |
| Cardurion Investigative Site | Allen | Texas | 75013 | — |
| Cardurion Investigative Site | Norfolk | Virginia | 23504 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05409183, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 19, 2024 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05409183 live on ClinicalTrials.gov.