Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea
Public ClinicalTrials.gov record NCT05412004. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol to Investigate the Efficacy and Safety of Tirzepatide Once Weekly in Participants Who Have Obstructive Sleep Apnea and Obesity: A Randomized, Double-Blind, Placebo-Controlled Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effect and safety of tirzepatide in participants with moderate to severe obstructive sleep apnea and obesity who are both unwilling or unable to use Positive Airway Pressure (PAP) therapy in GPI1 and those who are and plan to stay on PAP therapy in GPI2.
Study identification
- NCT ID
- NCT05412004
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 469 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 21, 2022 (Actual)
- Primary completion
- Mar 12, 2024 (Actual)
- Completion
- Mar 29, 2024 (Actual)
- Last update posted
- Apr 30, 2025
2022 – 2024
United States locations
- U.S. sites
- 18
- U.S. states
- 10
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Teradan Clinical Trials, LLC | Brandon | Florida | 33511 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| NeuroTrials Research Inc | Atlanta | Georgia | 30328 | — |
| Rocky Mountain Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Brengle Family Medicine | Indianapolis | Indiana | 46260 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| NeuroScience Research Center | Canton | Ohio | 44718 | — |
| CTI-CRC | Cincinnati | Ohio | 45212 | — |
| Office 18 | Pittsburgh | Pennsylvania | 15236 | — |
| Preferred Primary Care Physicians | Uniontown | Pennsylvania | 15401 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| Gadolin Research | Beaumont | Texas | 77702 | — |
| Advanced Neuro Research Center - ANRC | El Paso | Texas | 79912 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
| Sleep Therapy Research Center | San Antonio | Texas | 78229 | — |
| Rainier Clinical Research Center | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05412004, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 30, 2025 · Synced Nov 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05412004 live on ClinicalTrials.gov.