Study of ARO-APOC3 in Adults With Dyslipidemia
Public ClinicalTrials.gov record NCT05413135. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of ARO-APOC3 in Adults With Dyslipidemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an open-label extension of the parent studies AROAPOC3-2001 and AROAPOC3-2002. Adult participants with dyslipidemia who completed the blinded 12-month period from either parent study and continued to meet eligibility criteria had the option to be enrolled into this study. Eligible enrolled participants initially received open-label ARO-APOC3 every three or six months at the assigned dose level of the parent study until a final dose of 25 mg was selected, at which point all participants transitioned to the selected dosing regimen of 25 mg every 3 months.
Study identification
- NCT ID
- NCT05413135
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 418 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 6, 2022
- Primary completion
- Sep 21, 2025
- Completion
- Sep 21, 2025
- Last update posted
- May 11, 2026
2022 – 2025
United States locations
- U.S. sites
- 30
- U.S. states
- 16
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site 1 | Beverly Hills | California | 90211 | — |
| Clinical Research Site 2 | Northridge | California | 91325 | — |
| Clinical Research Site 3 | Palm Springs | California | 92292 | — |
| Clincal Research Site 4 | Boca Raton | Florida | 33434 | — |
| Clinical Research Site 5 | Fort Lauderdale | Florida | 33308 | — |
| Clinical Research Site 8 | Miami | Florida | 33155 | — |
| Clinical Research Site 6 | Miami | Florida | 33173 | — |
| Clinical Research Site 9 | Miami Springs | Florida | 33166 | — |
| Clinical Research Site 10 | Pembroke Pines | Florida | 33024 | — |
| Clinical Research Site 11 | Port Orange | Florida | 32127 | — |
| Clinical Research Site 12 | Dunwoody | Georgia | 30338 | — |
| Clinical Research Site 13 | Minneapolis | Minnesota | 55455 | — |
| Clinical Research Site 14 | Tupelo | Mississippi | 38801 | — |
| Clinical Research Site 15 | Omaha | Nebraska | 68114 | — |
| Clinical Research Site 16 | Las Vegas | Nevada | 89121 | — |
| Clinical Research Site 17 | Long Island City | New York | 11106 | — |
| Clinical Research Site 18 | New Windsor | New York | 12553 | — |
| Clinical Research Site 19 | New York | New York | 10029 | — |
| Clinical Research Site 20 | Morehead City | North Carolina | 28557 | — |
| Clinical Research Site 21 | Fargo | North Dakota | 58104 | — |
| Clinical Research Site 22 | Marion | Ohio | 43302 | — |
| Clinical Research Site 23 | Maumee | Ohio | 43537 | — |
| Clinical Research Site 24 | Oklahoma City | Oklahoma | 73135 | — |
| Clinical Research Site 25 | Greenville | South Carolina | 29607 | — |
| Clinical Research Site 26 | Chattanooga | Tennessee | 37421 | — |
| Clinical Research Site 29 | Houston | Texas | 77002 | — |
| Clinical Research Site 27 | Houston | Texas | 77030 | — |
| Clinical Research Site 28 | Houston | Texas | 77099 | — |
| Clinical Research Site 30 | San Antonio | Texas | 78249 | — |
| Clinical Research Site 31 | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05413135, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2026 · Synced Sep 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05413135 live on ClinicalTrials.gov.