Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis
Public ClinicalTrials.gov record NCT05415137. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, double-blind, placebo-controlled, study comparing the efficacy and safety of intravenous (IV) efzofitimod 3 mg/kg and 5 mg/kg versus placebo after 48 weeks of treatment. This study will enroll adults with histologically confirmed pulmonary sarcoidosis receiving stable treatment with oral corticosteroid (OCS), with or without immunosuppressant therapy.
Study identification
- NCT ID
- NCT05415137
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 268 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2022 (Actual)
- Primary completion
- Jun 25, 2025 (Actual)
- Completion
- Jul 14, 2025 (Actual)
- Last update posted
- Jun 4, 2026
2022 – 2025
United States locations
- U.S. sites
- 39
- U.S. states
- 27
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| aTyr Investigative Site | Birmingham | Alabama | 35294 | — |
| aTyr Investigative Site | Phoenix | Arizona | 85027 | — |
| aTyr Investigative Site | Los Angeles | California | 90033 | — |
| aTyr Investigative Site | Sacramento | California | 95817 | — |
| aTyr Investigative Site | Denver | Colorado | 80206 | — |
| aTyr Investigative Site | Washington D.C. | District of Columbia | 20060 | — |
| aTyr Investigative Site | Gainesville | Florida | 32610 | — |
| aTyr Investigative Site | Tampa | Florida | 33606 | — |
| aTyr Investigative Site | Weston | Florida | 33331 | — |
| aTyr Investigative Site | Atlanta | Georgia | 30308 | — |
| aTyr Investigative Site | Chicago | Illinois | 60611 | — |
| aTyr Investigative Site | Chicago | Illinois | 60612 | — |
| aTyr Investigative Site | Louisville | Kentucky | 40202 | — |
| aTyr Investigative Site | New Orleans | Louisiana | 70115 | — |
| aTyr Investigative Site | Baltimore | Maryland | 21224 | — |
| aTyr Investigative Site | Boston | Massachusetts | 02114 | — |
| aTyr Investigative Site | Ada | Michigan | 49301 | — |
| aTyr Investigative Site | Detroit | Michigan | 48202 | — |
| aTyr Investigative Site | Minneapolis | Minnesota | 55455 | — |
| aTyr Investigative Site | Rochester | Minnesota | 55905 | — |
| aTyr Investigative Site | Jackson | Mississippi | 39216 | — |
| aTyr Investigative Site | St Louis | Missouri | 63110 | — |
| aTyr Investigative Site | Albany | New York | 12208 | — |
| aTyr Investigative Site | Middletown | New York | 10941 | — |
| aTyr Investigative Site | Durham | North Carolina | 27710 | — |
| aTyr Investigative Site | Greenville | North Carolina | 27834 | — |
| aTyr Investigative Site | Cincinnati | Ohio | 45219 | — |
| aTyr Investigative Site | Cleveland | Ohio | 44195 | — |
| aTyr Investigative Site | Oklahoma City | Oklahoma | 73104 | — |
| aTyr Investigative Site | Portland | Oregon | 97220 | — |
| aTyr Investigative Site | Philadelphia | Pennsylvania | 19140 | — |
| aTyr Investigative Site | Charleston | South Carolina | 29425-0630 | — |
| aTyr Investigative Site | Dickson | Tennessee | 37055 | — |
| aTyr Investigative Site | Dallas | Texas | 75246 | — |
| aTyr Investigative Site | Dallas | Texas | 75390 | — |
| aTyr Investigative Site | Houston | Texas | 77030 | — |
| aTyr Investigative Site | Salt Lake City | Utah | 84132 | — |
| aTyr Investigative Site | Falls Church | Virginia | 22042 | — |
| aTyr Investigative Site | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05415137, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05415137 live on ClinicalTrials.gov.