A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson's Disease
Public ClinicalTrials.gov record NCT05424276. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of IkT-148009 in Untreated Parkinson's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study investigates the safety and tolerability of drug IkT-148009 in untreated Parkinson's disease volunteers (30 to 80 years old). It also looks at the pharmacokinetics of IkT-148009 in the body and evaluates the effect of IkT-148009 on motor and non-motor features of the disease. This 12 week study is designed to be 3:1 randomized across 3 doses of IkT-148009 or placebo. Each participant will self-administer one of 3 doses or placebo of IkT-148009 once daily (QD) with food for 12 weeks. For more information, visit our website: www.the201trial.com
Study identification
- NCT ID
- NCT05424276
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 137 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 15, 2023 (Actual)
- Primary completion
- Oct 25, 2024 (Actual)
- Completion
- Sep 13, 2025 (Actual)
- Last update posted
- Nov 19, 2025
2023 – 2025
United States locations
- U.S. sites
- 28
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neurology | Scottsdale | Arizona | 85258 | — |
| Neurology | Little Rock | Arkansas | 72205 | — |
| Neurology | Reseda | California | 91335 | — |
| Neurology | Stamford | Connecticut | 06905 | — |
| Neurologist | Boca Raton | Florida | 33486 | — |
| Neurology | Miami | Florida | 33136 | — |
| Neurology | Naples | Florida | 34105 | — |
| Neurology | Tampa | Florida | 33609 | — |
| Neurology | Tampa | Florida | 33613 | — |
| Neurology | Foxborough | Massachusetts | 02035 | — |
| Neurology | South Dartmouth | Massachusetts | 02747 | — |
| Neurology | Farmington Hills | Michigan | 48334 | — |
| Neurology | Golden Valley | Minnesota | 55427 | — |
| Neurology | West Long Branch | New Jersey | 07764 | — |
| Neurology | Durham | North Carolina | 27705 | — |
| Neurology | Raleigh | North Carolina | 27607 | — |
| Neurology | Columbus | Ohio | 43221 | — |
| Neurology | Tulsa | Oklahoma | 74136 | — |
| Neurology | Portland | Oregon | 97239 | — |
| Neurology | Port Royal | South Carolina | 29935 | — |
| Neurology | Memphis | Tennessee | 38137 | — |
| Neurology | Nashville | Tennessee | 37232 | — |
| Neurology | Frisco | Texas | 75035 | — |
| Neurology | Houston | Texas | 77030 | — |
| Neurology | Round Rock | Texas | 78681 | — |
| Neurology | Kirkland | Washington | 98034 | — |
| Neurology | Madison | Wisconsin | 53705 | — |
| Neurology | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05424276, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2025 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05424276 live on ClinicalTrials.gov.