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Terminated Phase 2 Interventional Results available

Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension Study

ClinicalTrials.gov ID: NCT05430854

Public ClinicalTrials.gov record NCT05430854. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 4:20 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Extension Study To Evaluate The Long- Term Safety And Tolerability Of Daxdilimab (Hzn-7734) In Subjects With Systemic Lupus Erythematosus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A Phase 2, Open-Label Extension study to evaluate the long-term safety and tolerability of daxdilimab in participants with Systemic Lupus Erythematosus completing the treatment period of the RECAST SLE clinical study.

Study identification

NCT ID
NCT05430854
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
155 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years to 72 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2022
Primary completion
Oct 30, 2023
Completion
Oct 30, 2023
Last update posted
Sep 18, 2024

2022 – 2023

United States locations

U.S. sites
14
U.S. states
9
U.S. cities
14
Facility City State ZIP Site status
Inland Rheumatology Clinical Trials Incorporated Upland California 91786
Clinical Research of West Florida Inc - Clearwater Clearwater Florida 33765-2616
Millennium Research Ormond Beach Florida 32174
IRIS Research and Development LLC Plantation Florida 33324
Clinical Research of West Florida Inc - Tampa Tampa Florida 33606-1246
Emory University School of Medicine Atlanta Georgia 30322
Bluegrass Community Research Inc Lexington Kentucky 40504-2931
NYU Langone Ambulatory Care Brooklyn Heights Brooklyn New York 11201
DJL Clinical Research Charlotte North Carolina 28210-8509
Paramount Medical Research and Consulting LLC Middleburg Heights Ohio 44130-3483
Precision Comprehensive Clinical Research Solutions Colleyville Texas 76034-5913
Metroplex Clinical Research Center Dallas Texas 75231
Southwest Rheumatology Research, LLC Mesquite Texas 75150
Spectrum Medical, Inc Danville Virginia 24541-1222

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05430854, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 18, 2024 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05430854 live on ClinicalTrials.gov.

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