THUNDER: Acute Ischemic Stroke Study With the Penumbra System® Including Thunderbolt™ Aspiration Tubing
Public ClinicalTrials.gov record NCT05437055. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to demonstrate the safety and efficacy of the Penumbra System including Thunderbolt Aspiration Tubing (Thunderbolt) in a population presenting with acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion (LVO) who are eligible for mechanical thrombectomy.
Study identification
- NCT ID
- NCT05437055
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 216 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 11, 2022 (Actual)
- Primary completion
- Sep 23, 2024 (Actual)
- Completion
- Dec 10, 2024 (Actual)
- Last update posted
- Jun 30, 2026
2022 – 2024
United States locations
- U.S. sites
- 32
- U.S. states
- 22
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Abrazo West Campus | Goodyear | Arizona | 85395 | — |
| Sharp Grossmont | San Diego | California | 92123 | — |
| HRI - Swedish | Englewood | Colorado | 80113 | — |
| Yale New Haven | New Haven | Connecticut | 06520 | — |
| Christiana Care | Newark | Delaware | 19718 | — |
| Jackson Memorial (U. of Miami) | Miami | Florida | 33136 | — |
| St. Joseph - BayCare | Tampa | Florida | 33614 | — |
| Piedmont Hospital Atlanta | Atlanta | Georgia | 30309 | — |
| Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| North Shore U. | Evanston | Illinois | 60201 | — |
| Edward Elmhurst Health | Naperville | Illinois | 60540 | — |
| Indiana U. Health | Indianapolis | Indiana | 46202 | — |
| KUMC | Kansas City | Kansas | 66160 | — |
| Massachusetts General | Boston | Massachusetts | 02114 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Abbott Northwestern | Minneapolis | Minnesota | 55427 | — |
| St. Dominic | Jackson | Mississippi | 39216 | — |
| Nebraska Medical | Omaha | Nebraska | 68198 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| University of Buffalo | Buffalo | New York | 14203 | — |
| Stonybrook U. | Stony Brook | New York | 11794 | — |
| New Hanover Regional | Wilmington | North Carolina | 28401 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Wellspan York | York | Pennsylvania | 17403 | — |
| MUSC | Charleston | South Carolina | 29425 | — |
| Fort Sanders | Knoxville | Tennessee | 37916 | — |
| Methodist U. | Memphis | Tennessee | 38104 | — |
| UT Houston | Houston | Texas | 77030 | — |
| Christus Trinity Medical Center | Tyler | Texas | 75702 | — |
| Riverside Regional Medical Center | Newport News | Virginia | 23601 | — |
| Valley Medical Center | Renton | Washington | 98055 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05437055, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 30, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05437055 live on ClinicalTrials.gov.