A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia
Public ClinicalTrials.gov record NCT05443724. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 52-week, Phase 2, Open-label Trial to Evaluate the Long-term Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to assess the long-term safety and tolerability of oral emraclidine in adult participants with schizophrenia.
Study identification
- NCT ID
- NCT05443724
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 698 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 1, 2022 (Actual)
- Primary completion
- Jun 25, 2025 (Actual)
- Completion
- Jun 25, 2025 (Actual)
- Last update posted
- Aug 21, 2026
2022 – 2025
United States locations
- U.S. sites
- 62
- U.S. states
- 18
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix, Arizona | Phoenix | Arizona | 85012-2707 | — |
| Bryant, Arkansas | Bryant | Arkansas | 72022-9252 | — |
| Little Rock, Arkansas | Little Rock | Arkansas | 72211-3702 | — |
| Anaheim, California | Anaheim | California | 92805-5854 | — |
| Bellflower, California | Bellflower | California | 90706-7079 | — |
| Culver City, California | Culver City | California | 90230-6632 | — |
| Garden Grove, California | Garden Grove | California | 92845-2506 | — |
| La Habra, California | La Habra | California | 90631-3842 | — |
| Lemon Grove, California | Lemon Grove | California | 91945-2956 | — |
| Montclair, California | Montclair | California | 91763-2231 | — |
| Orange,California | Orange | California | 92868-4447 | — |
| Pico Rivera, California | Pico Rivera | California | 90660-4920 | — |
| Riverside, California | Riverside | California | 92506-3237 | — |
| San Diego, California | San Diego | California | 92103-2209 | — |
| San Diego, California | San Diego | California | 92121 | — |
| San Diego, California | San Diego | California | 92123 | — |
| Sherman Oaks, California | Sherman Oaks | California | 91403-1747 | — |
| Torrance, California | Torrance | California | 90502-4432 | — |
| Walnut Creek, California | Walnut Creek | California | 94549 | — |
| New Haven, Connecticut | New Haven | Connecticut | 06519-1109 | — |
| Bonita Springs,Florida | Bonita Springs | Florida | 34134-4154 | — |
| Fort Myers, Florida | Fort Myers | Florida | 33901-3711 | — |
| Hialeah, Florida | Hialeah | Florida | 33012-4648 | — |
| Hialeah, Florida | Hialeah | Florida | 33016-1814 | — |
| Miami, Florida | Miami | Florida | 33122-1335 | — |
| Miami, Florida | Miami | Florida | 33125-5114 | — |
| Miami, Florida | Miami | Florida | 33155 | — |
| Miami Lakes, Florida | Miami Lakes | Florida | 33016-1553 | — |
| Miami Lakes, Florida | Miami Lakes | Florida | 33016 | — |
| Miami Springs, Florida | Miami Springs | Florida | 33166-7225 | — |
| Oakland Park, Florida | Oakland Park | Florida | 33334-4135 | — |
| West Palm Beach, Florida | West Palm Beach | Florida | 33407-2015 | — |
| Atlanta, Georgia | Atlanta | Georgia | 30318-3102 | — |
| Atlanta, Georgia | Atlanta | Georgia | 30328-4018 | — |
| Atlanta, Georgia | Atlanta | Georgia | 30331 | — |
| Decatur, Georgia | Decatur | Georgia | 30030-3438 | — |
| Savannah,Georgia | Savannah | Georgia | 31405-5702 | — |
| Berwyn, Illinois | Berwyn | Illinois | 60402-2248 | — |
| Chicago, Illinois | Chicago | Illinois | 60611-3478 | — |
| Chicago, Illinois | Chicago | Illinois | 60622-1702 | — |
| Chicago, Illinois | Chicago | Illinois | 60623 | — |
| Chicago, Illinois | Chicago | Illinois | 60640-5017 | — |
| Chicago, Illinois | Chicago | Illinois | 60641-4023 | — |
| Marrero, Louisiana | Marrero | Louisiana | 70072-3083 | — |
| Shreveport, Louisiana | Shreveport | Louisiana | 71101-4603 | — |
| Gaithersburg, Maryland | Gaithersburg | Maryland | 20877-1409 | — |
| Flowood, Mississippi | Flowood | Mississippi | 39232-8016 | — |
| Las Vegas, Nevada | Las Vegas | Nevada | 89102-1972 | — |
| Berlin, New Jersey | Berlin | New Jersey | 08009 | — |
| Cedarhurst, New York | Cedarhurst | New York | 11516-1905 | — |
| New York, New York | New York | New York | 10036-4811 | — |
| Staten Island, New York | Staten Island | New York | 10314-1607 | — |
| Charlotte, North Carolina | Charlotte | North Carolina | 28211-4849 | — |
| North Canton, Ohio | North Canton | Ohio | 44718-2567 | — |
| Oklahoma City, Oklahoma | Oklahoma City | Oklahoma | 73102-1018 | — |
| Franklin,Tennessee | Franklin | Tennessee | 37067-5967 | — |
| Austin, Texas | Austin | Texas | 78754-5122 | — |
| DeSoto, Texas | DeSoto | Texas | 75115-2066 | — |
| Houston, Texas | Houston | Texas | 77043 | — |
| Houston, Texas | Houston | Texas | 77074 | — |
| Plano, Texas | Plano | Texas | 75093-0010 | — |
| Richardson, Texas | Richardson | Texas | 75080-3764 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05443724, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05443724 live on ClinicalTrials.gov.