ClinicalTrials.gov record
Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
ClinicalTrials.gov ID: NCT05445778
Public ClinicalTrials.gov record NCT05445778. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRα-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.
Study identification
- NCT ID
- NCT05445778
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 520 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 15, 2023 (Actual)
- Primary completion
- Apr 2027 (Estimated)
- Completion
- May 2032 (Estimated)
- Last update posted
- Jun 2, 2026
2023 – 2032
United States locations
- U.S. sites
- 74
- U.S. states
- 31
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Usa Mitchell Cancer Institute /ID# 269661 | Mobile | Alabama | 36604 | — |
| Honorhealth Virginia G. Piper Cancer Care Network - Biltmore /ID# 269987 | Phoenix | Arizona | 85016 | — |
| City of Hope - Orange County Lennar Foundation Cancer Center /ID# 269573 | Irvine | California | 92618 | — |
| Moores Cancer Center at UC San Diego /ID# 269564 | La Jolla | California | 92093 | — |
| Kaiser Permanente - Los Angeles Medical Center /ID# 269541 | Los Angeles | California | 90027 | — |
| University Of California Irvine Medical Center /ID# 269572 | Orange | California | 92868 | — |
| Stanford Women'S Cancer Center /ID# 269552 | Palo Alto | California | 94304 | — |
| Kaiser Permanente - Riverside Medical Center /ID# 269539 | Riverside | California | 92505 | — |
| Kaiser Permanente Zion Medical Center /ID# 269537 | San Diego | California | 92120 | — |
| Kaiser Permanente - San Diego Medical Center /ID# 269540 | San Diego | California | 92123 | — |
| Kaiser Permanente - San Marcos Medical Offices /ID# 269542 | San Marcos | California | 92069 | — |
| Olive View-Ucla Medical Center /ID# 269584 | Sylmar | California | 91342 | — |
| John Muir Health - Walnut Creek Medical Center /ID# 269575 | Walnut Creek | California | 94598 | — |
| Broward General Medical Center /ID# 269577 | Fort Lauderdale | Florida | 33316 | — |
| Regional Cancer Center /ID# 269558 | Fort Myers | Florida | 33905 | — |
| Baptist Md Anderson Cancer Center - Jacksonville - Palm Avenue /ID# 269560 | Jacksonville | Florida | 32207 | — |
| Mount Sinai Medical Center /ID# 269582 | Miami | Florida | 33140 | — |
| Sarasota Memorial Hospital /ID# 269526 | Sarasota | Florida | 34239 | — |
| Northside Hospital /ID# 269660 | Atlanta | Georgia | 30342 | — |
| Rush University Medical Center /ID# 269583 | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center /ID# 269546 | Chicago | Illinois | 60637 | — |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center /ID# 269110 | Indianapolis | Indiana | 46202-5116 | — |
| St. Vincent Indianapolis Hospital /ID# 269107 | Indianapolis | Indiana | 46260 | — |
| University of Iowa /ID# 269566 | Iowa City | Iowa | 52242 | — |
| The University of Kansas Cancer Center - Westwood /ID# 269106 | Westwood | Kansas | 66205 | — |
| Baptist Health Lexington /ID# 269568 | Lexington | Kentucky | 40503 | — |
| University of Kentucky Chandler Medical Center. /ID# 269536 | Lexington | Kentucky | 40536 | — |
| Louisiana State University Health Sciences Center - New Orleans /ID# 269559 | New Orleans | Louisiana | 70112 | — |
| Ochsner Medical Center - Jefferson Highway /ID# 269530 | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center - Scarborough Campus /ID# 269555 | Scarborough | Maine | 04074 | — |
| Johns Hopkins Hospital /ID# 269579 | Baltimore | Maryland | 21287 | — |
| Sinai Hospital Of Baltimore /ID# 269567 | Manchester | Maryland | 21215 | — |
| GBMC Cancer Center /ID# 269561 | Towson | Maryland | 21204-6831 | — |
| Tufts Medical Center /ID# 269547 | Boston | Massachusetts | 02111-1552 | — |
| Baystate Medical Center /ID# 269544 | Springfield | Massachusetts | 01199 | — |
| Corewell Health /ID# 269562 | Grand Rapids | Michigan | 49503 | — |
| Minnesota Oncology - Coon Rapids Clinic /ID# 269550 | Coon Rapids | Minnesota | 55433 | — |
| Nebraska Methodist Hospital /ID# 269580 | Omaha | Nebraska | 68114 | — |
| The Center Of Hope /ID# 269528 | Reno | Nevada | 89511 | — |
| Dartmouth-Hitchcock Medical Center /ID# 269576 | Lebanon | New Hampshire | 03756 | — |
| John Theurer Cancer Center /ID# 269109 | Hackensack | New Jersey | 07601 | — |
| The Valley Hospital /ID# 269548 | Paramus | New Jersey | 07652 | — |
| Holy Name Medical Center /ID# 269543 | Teaneck | New Jersey | 07666 | — |
| New York Oncology Hematology - Albany Cancer Center /ID# 269565 | Albany | New York | 12206-5013 | — |
| Women'S Cancer Care Associates /ID# 269553 | Albany | New York | 12208 | — |
| Northwell Health Center for Advanced Medicine. /ID# 269108 | Lake Success | New York | 11042 | — |
| Perlmutter Cancer Center at NYU Langone Hematology Oncology Associates - Mineola /ID# 269534 | Mineola | New York | 11501 | — |
| NYU Laura and Isaac Perlmutter Cancer Center /ID# 269556 | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai /ID# 269529 | New York | New York | 10029 | — |
| University of North Carolina at Chapel Hill /ID# 269563 | Chapel Hill | North Carolina | 27514 | — |
| Duke Cancer Institute /ID# 269557 | Durham | North Carolina | 27710 | — |
| University of Cincinnati /ID# 269578 | Cincinnati | Ohio | 45267-2827 | — |
| Jamescare Gynecologic Oncology At Mill Run /ID# 269105 | Hilliard | Ohio | 43026 | — |
| Kettering Medical Center /ID# 269585 | Kettering | Ohio | 45429 | — |
| OU Health - Stephenson Cancer Center /ID# 269525 | Oklahoma City | Oklahoma | 73104 | — |
| Oklahoma Cancer Specialists and Research Institute /ID# 269527 | Tulsa | Oklahoma | 74146 | — |
| Willamette Valley Cancer Institute and Research Center /ID# 269988 | Eugene | Oregon | 97401 | — |
| Compass Oncology - Rose Quarter /ID# 270131 | Portland | Oregon | 97227 | — |
| Oregon Health and Science University /ID# 269581 | Portland | Oregon | 97239 | — |
| University Of Pittsburgh Medical Center Magee - Womens Hospital /ID# 269659 | Pittsburgh | Pennsylvania | 15213 | — |
| Allegheny Health Network West Penn Hospital /ID# 269551 | Pittsburgh | Pennsylvania | 15244 | — |
| Asplundh Cancer Pavilion /ID# 269574 | Willow Grove | Pennsylvania | 19090 | — |
| Sanford Cancer Center /ID# 269535 | Sioux Falls | South Dakota | 57104 | — |
| West Cancer Center and Research Institute - Germantown /ID# 269569 | Germantown | Tennessee | 38138 | — |
| Texas Oncology - Austin Central /ID# 269531 | Austin | Texas | 78731 | — |
| Texas Oncology - Bedford /ID# 269571 | Bedford | Texas | 76022 | — |
| Texas Oncology - Methodist Dallas Cancer Center /ID# 269554 | Dallas | Texas | 75203 | — |
| Texas Oncology - Fort Worth Cancer Center /ID# 269532 | Fort Worth | Texas | 76104 | — |
| US Oncology Research Investigational Products Center /ID# 278746 | Irving | Texas | 75063 | — |
| Texas Oncology - San Antonio Medical Center - Research Drive /ID# 269549 | San Antonio | Texas | 78240 | — |
| University of Virginia Health System /ID# 269545 | Charlottesville | Virginia | 22908-0816 | — |
| Virginia Oncology Associates - Norfolk (Lake Wright) /ID# 269533 | Norfolk | Virginia | 23502 | — |
| VCU Health Adult Outpatient Pavillion /ID# 269570 | Richmond | Virginia | 23219 | — |
| Swedish Cancer Institute /ID# 269538 | Seattle | Washington | 98104-3588 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 190 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05445778, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 2, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05445778 live on ClinicalTrials.gov.