Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee
Public ClinicalTrials.gov record NCT05449132. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Phase III Trial, to Evaluate the Efficacy and Safety of a Single Intra-articular Injection of RTX-GRT7039 in Adult Subjects With Pain Associated With Osteoarthritis of the Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A double-blind, randomized, placebo-controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of single injection of RTX-GRT7039 versus placebo in patients who have pain associated with osteoarthritis of the knee despite standard of care.
Study identification
- NCT ID
- NCT05449132
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 466 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 26, 2022 (Actual)
- Primary completion
- Aug 15, 2024 (Actual)
- Completion
- Aug 15, 2024 (Actual)
- Last update posted
- Mar 18, 2026
2022 – 2024
United States locations
- U.S. sites
- 56
- U.S. states
- 22
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Achieve Clinical Research, LLC | Birmingham | Alabama | 35216 | — |
| Arizona Arthritis and Rheumatology Associates (AARA) P.C | Glendale | Arizona | 85351 | — |
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Tucson Orthopaedic Research Center | Tucson | Arizona | 85712 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| Core Health Care Group | Cerritos | California | 90703 | — |
| Acclaim Clinical Research, Inc. | San Diego | California | 92120 | — |
| Dr. Hans Richard Barthel, MD Office Of | Santa Barbara | California | 93108 | — |
| Medvin Clinical Research | Thousand Oaks | California | 91360 | — |
| Westlake Medical Research | Thousand Oaks | California | 91360 | — |
| Allied Biomedical Research Institute | Miami | Florida | 33155 | — |
| Well Pharma Medical Research, Corp. | Miami | Florida | 33173 | — |
| Sensible Healthcare LLC | Ocoee | Florida | 34761 | — |
| Clinical Neuroscience Solutions, Inc. dba CNS Healthcare | Orlando | Florida | 32801 | — |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32806 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Gulfcoast Research Institute | Sarasota | Florida | 34232 | — |
| Better Health Clinical Research, Inc. | Newnan | Georgia | 30265 | — |
| Vista Clinical Research | Newnan | Georgia | 30265 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Injury Care Research | Boise | Idaho | 83713 | — |
| Chicago Clinical Research Institute Inc. | Chicago | Illinois | 60607 | — |
| Chicago Medical Research, LLC | Hazel Crest | Illinois | 60429 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| Neuroscience Research Center, LLC | Overland Park | Kansas | 66210 | — |
| DelRicht Research | New Orleans | Louisiana | 70124 | — |
| LCMC Health Urgent Care - Lakeview | New Orleans | Louisiana | 70124 | — |
| June DO,PC | Lansing | Michigan | 48911 | — |
| Oakland Medical Research Center | Troy | Michigan | 48085 | — |
| Sundance Clinical Research, LLC | St Louis | Missouri | 63141 | — |
| Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| Las Vegas Clinical Trials, LLC | North Las Vegas | Nevada | 89030 | — |
| Albuquerque Clinical Trials, Inc. | Albuquerque | New Mexico | 87102 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| Upstate Clinical Research Associates | Williamsville | New York | 14221 | — |
| Accellacare Research of Charlotte | Charlotte | North Carolina | 28209 | — |
| Park Road Medical Clinic | Charlotte | North Carolina | 28211 | — |
| Accellacare of Raleigh | Raleigh | North Carolina | 27609 | — |
| Raleigh Medical Group | Raleigh | North Carolina | 27609 | — |
| Accellacare Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Gastroenterology Associates of the Piedmont | Winston-Salem | North Carolina | 27103 | — |
| The Center For Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| University Orthopedics Center | Altoona | Pennsylvania | 16602 | — |
| University Orthopedics Center | Altoona | Pennsylvania | 9421166 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Antria Inc. | Indiana | Pennsylvania | 15701 | — |
| Arthritis Group | Philadelphia | Pennsylvania | 19152-3303 | — |
| University Orthopedics Center | State College | Pennsylvania | 16801 | — |
| Chan Soon-Shiong Medical Center at Windber | Windber | Pennsylvania | 15963 | — |
| PCPMG Clinical Research Unit, LLC | Greenville | South Carolina | 29601 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Health Concepts | Rapid City | South Dakota | 57702 | — |
| Accellacare - Knoxville | Knoxville | Tennessee | 37912 | — |
| Wasatch Clinical Research | Salt Lake City | Utah | 84107 | — |
| Charlottesville Medical Research Center LLC | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05449132, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 18, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05449132 live on ClinicalTrials.gov.