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Completed Phase 1 Interventional Results available

Multiple Rising Dose Study of MK-6194 in Participants With Atopic Dermatitis (MK-6194-008)

ClinicalTrials.gov ID: NCT05450198

Public ClinicalTrials.gov record NCT05450198. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 1:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Multiple Rising Dose Clinical Trial to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-6194 in Participants With Moderate to Severe Atopic Dermatitis

Study identification

NCT ID
NCT05450198
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
72 participants

Conditions and interventions

Interventions

  • MK-6194 Biological
  • Placebo Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 7, 2022
Primary completion
May 21, 2024
Completion
May 21, 2024
Last update posted
Jun 4, 2025

2022 – 2024

United States locations

U.S. sites
13
U.S. states
8
U.S. cities
12
Facility City State ZIP Site status
Arkansas Research Trials-Clinical Trials ( Site 0002) North Little Rock Arkansas 72117
Miami Dermatology and Laser Research ( Site 0025) Miami Florida 33173
Global Health Research Center, Inc. ( Site 0005) Miami Lakes Florida 33016
Genesis Clinical Research, LLC ( Site 0004) Tampa Florida 33603
ForCare Clinical Research ( Site 0003) Tampa Florida 33613
Advanced Medical Research, PC. ( Site 0027) Sandy Springs Georgia 30328
AXIS Clinicals ( Site 0029) Dilworth Minnesota 56529
Remington Davis Clinical Research ( Site 0021) Columbus Ohio 43215
Paddington Testing Company ( Site 0010) Philadelphia Pennsylvania 19103
North Texas Center for Clinical Research ( Site 0028) Frisco Texas 75034
Progressive Clinical Research ( Site 0022) San Antonio Texas 78213
Complete Dermatology ( Site 0023) Sugar Land Texas 77478
Premier Clinical Research ( Site 0026) Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05450198, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 4, 2025 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05450198 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →