A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa
Public ClinicalTrials.gov record NCT05453578. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/2, Multi-Centered, Randomized, Double-Blind, Placebo-Controlled Trial of the Safety and Microbiological Activity of a Single Dose of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa
Study identification
- NCT ID
- NCT05453578
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 73 participants
Conditions and interventions
Conditions
Interventions
- Placebo Other
- WRAIR-PAM-CF1 Biological
Other · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2, 2022
- Primary completion
- Apr 9, 2025
- Completion
- Apr 9, 2025
- Last update posted
- Jul 15, 2026
2022 – 2025
United States locations
- U.S. sites
- 19
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Arizona - Banner University Medical Center Tucson Campus - Tucson | Tucson | Arizona | 85724-0001 | — |
| University of California, San Diego | La Jolla | California | 92037 | — |
| University of California, San Diego (UCSD) - Antiviral Research Center (AVRC) | La Jolla | California | 92121 | — |
| University of California Los Angeles Medical Center - Westwood Clinic | Los Angeles | California | 90095 | — |
| University of California Davis Health | Sacramento | California | 95816 | — |
| Stanford University | Stanford | California | 94305 | — |
| Yale North Haven Medical Center- Winchester Center for Lung Disease | North Haven | Connecticut | 06473 | — |
| University of South Florida/Tampa General Hospital | Tampa | Florida | 22612 | — |
| Emory University - Adult Cystic Fibrosis Program | Atlanta | Georgia | 30324 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 55455-0341 | — |
| Northwell Health | New Hyde Park | New York | 11050 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor College of Medicine | Houston | Texas | 77030-3411 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05453578, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 15, 2026 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05453578 live on ClinicalTrials.gov.