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Completed Phase 2 Interventional Results available

Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124

ClinicalTrials.gov ID: NCT05459688

Public ClinicalTrials.gov record NCT05459688. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 30, 2026, 4:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124 to Evaluate the Long-Term Safety and Effectiveness of CIN-107

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 2, multicenter, open-label extension (OLE) study to evaluate the long-term safety, tolerability, and effectiveness of CIN-107 for up to 52 weeks in patients with HTN who have completed Part 1 or Part 2 of Study CIN-107-124. The study will be conducted at clinical sites that have participated in the double-blind, Phase 2 Study CIN-107-124.

Study identification

NCT ID
NCT05459688
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
175 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 100 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 6, 2022 (Actual)
Primary completion
Nov 7, 2023 (Actual)
Completion
Nov 7, 2023 (Actual)
Last update posted
Dec 16, 2024

2022 – 2023

United States locations

U.S. sites
36
U.S. states
14
U.S. cities
35
Facility City State ZIP Site status
Research Site Saraland Alabama 36571 —
Research Site Huntington Park California 90255 —
Research Site Lincoln California 95648 —
Research Site Los Angeles California 90057 —
Research Site Northridge California 91324 —
Research Site Oceanside California 92056 —
Research Site Panorama City California 91402 —
Research Site Van Nuys California 91405 —
Research Site Clearwater Florida 33765 —
Research Site Doral Florida 33166 —
Research Site Hialeah Florida 33012 —
Research Site Hollywood Florida 33024 —
Research Site Lake Worth Florida 33467 —
Research Site Miami Florida 33165 —
Research Site Miami Florida 33173 —
Research Site Pembroke Pines Florida 33027 —
Research Site Winter Haven Florida 33880 —
Research Site Addison Illinois 60101 —
Research Site Chicago Illinois 60607 —
Research Site Morton Illinois 61550 —
Research Site Brownsburg Indiana 46112 —
Research Site New Orleans Louisiana 70124 —
Research Site Troy Michigan 48085 —
Research Site Olive Branch Mississippi 38654 —
Research Site Brooklyn New York 11235 —
Research Site Columbus Ohio 43213 —
Research Site Edmond Oklahoma 73013 —
Research Site Austin Texas 78705 —
Research Site Carrollton Texas 75006 —
Research Site Dallas Texas 75234 —
Research Site Georgetown Texas 78628 —
Research Site Houston Texas 77040 —
Research Site Lampasas Texas 76550 —
Research Site San Antonio Texas 78209 —
Research Site West Valley City Utah 84120 —
Research Site Manassas Virginia 20110 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05459688, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 16, 2024 · Synced Oct 30, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05459688 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →