Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
Public ClinicalTrials.gov record NCT05461092. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This initial study is a feasibility study for implementing thoracolumbar interfascial plane, or TLIP, blocks in older adults undergoing spinal fusion. TLIP blocks are done by using anesthesia. In this case, it will be done to either side of the back where surgery will be performed. This has been shown to decrease pain the patients have post-operatively in previous research. In this study, the investigators will examine recruitment rates, completion of assessments, dropout rate, gather patient feedback, and identify barriers to performing TLIP. Further, this feasibility study will provide data to determine adequate sample size and refine methods and outcomes for a future randomized clinical trial. The ultimate goal is to perform a large, appropriately powered randomized control trial to determine the effect of TLIP blocks on pain, physical function and disability, opioid consumption, and delirium in older adult undergoing spinal fusion.
Study identification
- NCT ID
- NCT05461092
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Early Phase 1
- Enrollment
- 50 participants
Conditions and interventions
Interventions
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine Drug
- Blood Test Diagnostic Test
- 3D CAM Delirium Severity Scoring Other
- Generalized Anxiety Disorder 7-item (GAD-7) scale Other
- Numerical Rating Score (NRS) Other
- PROMIS-Pain Interference Other
- Oswestry Disability Index (ODI) Other
- Saint Louis University Mental Status Examination (SLUMs) Other
- Delirium Rating Scale-Revised-98 (DRS) Other
- Telephone Interview for Cognitive Status - Modified (TICS-M) Other
- Opioid Equivalents measured by Morphine Milligram Equivalents (MME) Other
- Patient Health Questionnaire depression scale (PHQ-8) Other
- Pain Catastrophizing Other
- Fear Avoidance Beliefs Questionnaire (FABQ) Other
- Opioid Side Effects and Likeability Questionnaire Other
- Daily Pain Trajectory Other
- Tampa Scale of Kinesiophobia Other
- Quality of Recovery 15 Other
Drug · Diagnostic Test · Other
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2023
- Primary completion
- Dec 30, 2026
- Completion
- Dec 30, 2026
- Last update posted
- Mar 26, 2026
2024 – 2026
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Iowa | Iowa City | Iowa | 52242 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05461092, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05461092 live on ClinicalTrials.gov.