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Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study to Compare the Immunogenicity and Safety of 3 Lots of NVX-CoV2373 in Adults

ClinicalTrials.gov ID: NCT05463068

Public ClinicalTrials.gov record NCT05463068. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 5:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Observer-Blinded, Phase 3 Study to Compare the Immunogenicity and Safety of 3 Lots of NVX-CoV2373 in Adults

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, Phase 3 study comparing the immunogenicity and safety of 3 different lots of Novavax vaccine with Matrix-M™ adjuvant (NVX-CoV2373).The study will enroll approximately 900 previously vaccinated adults 18 to 49 years of age, inclusive.

Study identification

NCT ID
NCT05463068
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novavax
Industry
Enrollment
911 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 49 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 10, 2022
Primary completion
Aug 16, 2022
Completion
Aug 31, 2022
Last update posted
Apr 16, 2026

2022

United States locations

U.S. sites
30
U.S. states
16
U.S. cities
29
Facility City State ZIP Site status
Long Beach Clinical Trial Services Inc. Long Beach California 90806
Benchmark Research Sacramento California 95864
Accel Clinical Research DeLand Florida 32720
Research Centers of America Hollywood Florida 33024
Jacksonville Center for Clinical Research Jacksonville Florida 32216
Multi-Specialty Research Associates, Inc. Lake City Florida 32055
Cen/Excel ACMR Atlanta Georgia 30331
Meridian Clinical Research Savannah Georgia 31406
CRA Headlands Stockbridge Georgia 30281
Velocity Clinical Research Boise Idaho 83642
Meridian Clinical Research Sioux City Iowa 51106
Meridian Clinical Research Baton Rouge Louisiana 70809
MedPharmics Gulfport Mississippi 39503
Sundance Clinical Research St Louis Missouri 63141
Meridian Clinical Research Norfolk Nebraska 68701
Meridian Clinical Research Omaha Nebraska 68134
Meridian Clinical Research Endwell New York 13760
Rochester Clinical Research Rochester New York 14609
OnSite Clinical Solutions, LLC Charlotte North Carolina 28208
CTI Clinical Research Center Cincinnati Ohio 45212
Velocity Clinical Research Cleveland Ohio 44122
Lynn Health Science Institute Oklahoma City Oklahoma 73112
Tekton Research Yukon Oklahoma 73099
Velocity Clinical Research Grants Pass Oregon 97527
Velocity Clinical Research East Greenwich Rhode Island 02818
Benchmark Research Austin Texas 78705
Tekton Research Austin Texas 78747
Benchmark Research Houston Texas 76135
Research Your Health Plano Texas 75093
Tekton Research San Antonio Texas 78229

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05463068, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced Sep 5, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05463068 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →