Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction
Public ClinicalTrials.gov record NCT05464940. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction in Patients With Paroxysmal Atrial Fibrillation: The COFFEE-AF Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This "How caffeine Induces Atrial Tachyarrhythmias" trial will be a multi-center, randomized, double-blinded trial of intravenous caffeine versus placebo among patients undergoing pulmonary vein isolation procedures for Atrial Fibrillation(AF).
Study identification
- NCT ID
- NCT05464940
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2025
- Primary completion
- Feb 28, 2026
- Completion
- May 31, 2026
- Last update posted
- Aug 27, 2025
2025 – 2026
United States locations
- U.S. sites
- 9
- U.S. states
- 4
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Loma Linda University | Loma Linda | California | 92350 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Kansas City Heart Rhythm Institute | Overland Park | Kansas | 66211 | — |
| Overland Park Regional Medical Center | Overland Park | Kansas | 66215 | — |
| Centerpoint Medical Center Clinic | Independence | Missouri | 64057 | — |
| Centerpoint Medical Center | Independence | Missouri | 64057 | — |
| Research Medical Center Clinic | Kansas City | Missouri | 64032 | — |
| Research Medical Center | Kansas City | Missouri | 64032 | — |
| Texas Cardiac Arrythmia Institute | Austin | Texas | 78705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05464940, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 27, 2025 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05464940 live on ClinicalTrials.gov.