ClinicalTrials.gov record
CREST-2 Long-term Observational Extension Study
ClinicalTrials.gov ID: NCT05465122
Public ClinicalTrials.gov record NCT05465122. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical Trial
Study identification
- NCT ID
- NCT05465122
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Lead sponsor
- Mayo Clinic
- Other
- Enrollment
- 2,480 participants
Conditions and interventions
Conditions
Interventions
- Carotid Endarterectomy Procedure
- FDA-approved carotid stents Procedure
- Intensive Medical Management Other
Procedure · Other
Eligibility (public fields only)
- Age range
- 35 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 4, 2022
- Primary completion
- Aug 30, 2027
- Completion
- Aug 30, 2027
- Last update posted
- May 27, 2026
2022 – 2027
United States locations
- U.S. sites
- 61
- U.S. states
- 29
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Mayo Clinic Pheonix | Phoenix | Arizona | 85054 | — |
| Banner University Medical Center | Tucson | Arizona | 85724 | — |
| Central Arkansas VA | Little Rock | Arkansas | 72143 | — |
| Mission Cardiovascular Research Institute | Fremont | California | 94538 | — |
| Kaiser Permanente Los Angeles | Los Angeles | California | 90027 | — |
| USC/Keck Medical Center | Los Angeles | California | 90033 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| Kaiser Permanente Divsion of Research | San Francisco | California | 94115 | — |
| Kaiser Permanente San Francisco | San Francisco | California | 94115 | — |
| St. Joseph's Medical Center | Stockton | California | 95204 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 16520 | — |
| Morton Plant Mease Healthcare | Clearwater | Florida | 33756 | — |
| University of Florida Health at Shands | Gainesville | Florida | 32610 | — |
| Lyerly Neurosurgery/Baptist Health | Jacksonville | Florida | 32207 | — |
| University of Florida Jacksonville | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Miami Cardiac and Vascular Institute | Miami | Florida | 33176 | — |
| Cardiovascular Institute NW Florida | Panama City | Florida | 32405 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Endeavor Health/NorthShore University | Evanston | Illinois | 60201 | — |
| Prairie Heart/St. John's Hospital | Springfield | Illinois | 62701 | — |
| Deaconess Heart Group | Newburgh | Indiana | 47630 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| Baptist Health | Lexington | Kentucky | 40503 | — |
| Ochsner Health System | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| VA Medical Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University | Baltimore | Maryland | 21224 | — |
| White Oak Medical Center | Silver Spring | Maryland | 20904 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| St. Elizabeth's Medical Center | Boston | Massachusetts | 02135 | — |
| VA Ann Arbor | Ann Arbor | Michigan | 48105 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Michigan Vascular Center | Flint | Michigan | 48532 | — |
| Sparrow Clinical Research Institute | Lansing | Michigan | 48912 | — |
| Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| North Memorial Medical Center | Golden Valley | Minnesota | 55422 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Mercy Hospital | St Louis | Missouri | 63141 | — |
| SUNY Buffalo | Buffalo | New York | 14203 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| Crouse Hospital | Syracuse | New York | 13210 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| Mercy Health St. Vincent | Toledo | Ohio | 43608 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Pinnacle Health | Harrisburg | Pennsylvania | 17043 | — |
| Hospital of University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| VA Pittsburgh | Pittsburgh | Pennsylvania | 15240 | — |
| Berks Cardiologists | Wyomissing | Pennsylvania | 19610 | — |
| The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Wellmont CVA Heart Institute | Kingsport | Tennessee | 37660 | — |
| Tennova Healthcare | Knoxville | Tennessee | 37934 | — |
| Seton Medical Center | Austin | Texas | 78705 | — |
| University of Utah Hospitals & Clinics | Salt Lake City | Utah | 84132 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| VA Puget Sound | Seattle | Washington | 98108 | — |
| Gundersen Clinic, Ltd. | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05465122, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 27, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05465122 live on ClinicalTrials.gov.