Study to Assess the Efficacy and Safety of Orismilast in Atopic Dermatitis (ADESOS)
Public ClinicalTrials.gov record NCT05469464. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of Orismilast in Adults With Moderate to Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study investigates 3 different doses of orismilast modified release compared to placebo in adult patients with moderate-to-severe atopic dermatitis. The purpose of the study is to assess the effect of orismilast modified release in moderate-to-severe atopic dermatitis and assess the safety aspects of these 3 different doses. The patients will receive an oral treatment of either orismilast modified release tablets or placebo tablets 2 times a day for 16 weeks.
Study identification
- NCT ID
- NCT05469464
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 235 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 11, 2022 (Actual)
- Primary completion
- Jan 23, 2024 (Actual)
- Completion
- Feb 15, 2024 (Actual)
- Last update posted
- Mar 7, 2025
2022 – 2024
United States locations
- U.S. sites
- 18
- U.S. states
- 9
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| First OC Dermatology Research Inc | Fountain Valley | California | 92708 | — |
| Axon Clinical Research | Inglewood | California | 90301 | — |
| LA Universal Research Center, INC. | Los Angeles | California | 90057 | — |
| Acclaim Clinical Research Inc. | San Diego | California | 92120 | — |
| Advance Medical Research Center | Miami | Florida | 33135 | — |
| Clinical Research Trials of Florida ,Inc. | Tampa | Florida | 33607 | — |
| Alliance Clinical Research of Tampa | Tampa | Florida | 33615 | — |
| ALLCUTIS Research, LLC | Beverly | Massachusetts | 01915 | — |
| Revival Research Institute, LLC | Troy | Michigan | 48084 | — |
| Michigan Dermatology Institute | Waterford | Michigan | 48328 | — |
| Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| ALLCUTIS Research, LLC | Portsmouth | New Hampshire | 03801 | — |
| Juva Skin & Laser Center | New York | New York | 10022 | — |
| Sadick Research Group LLC | New York | New York | 10075 | — |
| Apex Clinical Research Center | Mayfield Heights | Ohio | 44124 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| Tranquility Research | Webster | Texas | 77598 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05469464, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 7, 2025 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05469464 live on ClinicalTrials.gov.