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Completed Phase 2 Interventional Results available

Study to Assess the Efficacy and Safety of Orismilast in Atopic Dermatitis (ADESOS)

ClinicalTrials.gov ID: NCT05469464

Public ClinicalTrials.gov record NCT05469464. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 3:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of Orismilast in Adults With Moderate to Severe Atopic Dermatitis

Study identification

NCT ID
NCT05469464
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
UNION therapeutics
Industry
Enrollment
235 participants

Conditions and interventions

Interventions

  • Orismilast modified release tablets Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 10, 2022
Primary completion
Jan 22, 2024
Completion
Feb 14, 2024
Last update posted
Mar 6, 2025

2022 – 2024

United States locations

U.S. sites
18
U.S. states
9
U.S. cities
16
Facility City State ZIP Site status
Hope Clinical Research Canoga Park California 91303
First OC Dermatology Research Inc Fountain Valley California 92708
Axon Clinical Research Inglewood California 90301
LA Universal Research Center, INC. Los Angeles California 90057
Acclaim Clinical Research Inc. San Diego California 92120
Advance Medical Research Center Miami Florida 33135
Clinical Research Trials of Florida ,Inc. Tampa Florida 33607
Alliance Clinical Research of Tampa Tampa Florida 33615
ALLCUTIS Research, LLC Beverly Massachusetts 01915
Revival Research Institute, LLC Troy Michigan 48084
Michigan Dermatology Institute Waterford Michigan 48328
Excel Clinical Research Las Vegas Nevada 89109
ALLCUTIS Research, LLC Portsmouth New Hampshire 03801
Juva Skin & Laser Center New York New York 10022
Sadick Research Group LLC New York New York 10075
Apex Clinical Research Center Mayfield Heights Ohio 44124
Clinical Trial Network Houston Texas 77074
Tranquility Research Webster Texas 77598

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05469464, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 6, 2025 · Synced May 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05469464 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →