Phase II Study to Assess Safety and Efficacy of SL-1002 for Osteoarthritic Knee Pain
Public ClinicalTrials.gov record NCT05470608. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Escalation Study to Assess the Safety and Efficacy of SL-1002 Injectable for Treatment of Knee Pain Associated With Osteoarthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, double-blind, placebo-controlled, single ascending dose escalation study to assess the safety and efficacy of single treatment exposure of an injectable formulation of SL-1002 for the treatment of knee pain associated with osteoarthritis. Phase A of the study will enroll 3 cohorts of 8 patients per cohort, for a total of 24 patients. Patients will be randomized to receive either SL-1002 or placebo in a 3:1 ratio within each given cohort. Phase B of the study will enroll a minimum of 92 up to a maximum of 108 patients. Patients will be randomized to receive either SL-1002 or placebo in a 3:1 ratio at the recommended dose determined from Phase A. The study period will be up to 168 days inclusive of a screening period of up to 28 days.
Study identification
- NCT ID
- NCT05470608
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 132 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 35 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 12, 2022
- Primary completion
- Dec 31, 2023
- Completion
- Dec 31, 2023
- Last update posted
- Aug 28, 2023
2022 – 2024
United States locations
- U.S. sites
- 15
- U.S. states
- 13
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Denver Spine & Pain Institute | Greenwood Village | Colorado | 80111 | — |
| International Spine, Pain & Performance Center | Washington D.C. | District of Columbia | 20006 | — |
| Prime Medical Research | Coral Gables | Florida | 33134 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Cooper Neurological Institute | Camden | New Jersey | 08103 | — |
| Center for Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| Pacific Sports and Spine | Eugene | Oregon | 97404 | — |
| University Orthopedics Center | Altoona | Pennsylvania | 16602 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Institute of Precision Pain Medicine | Corpus Christi | Texas | 78414 | — |
| Precision Spine Care | Tyler | Texas | 75701 | — |
| University of Utah School of Medicine | Salt Lake City | Utah | 84108 | — |
| Virginia iSpine Physicians | Richmond | Virginia | 23235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05470608, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 28, 2023 · Synced Sep 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05470608 live on ClinicalTrials.gov.