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Completed Phase 2 Interventional

EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA

ClinicalTrials.gov ID: NCT05480228

Public ClinicalTrials.gov record NCT05480228. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 5:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

EPPIC-Net EN21-01 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of 80 mg Daily of NRD135S.E1 Versus Placebo in Adult and Elderly Participants With Painful Diabetic Peripheral Neuropathy.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to investigate the safety and efficacy of the current hard gelatin capsule formulation of NRD135S.E1 80 mg once daily in the treatment of PDPN when administered for 13 weeks.

Study identification

NCT ID
NCT05480228
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
James P. Rathmell, MD
Other
Enrollment
127 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 20, 2022
Primary completion
Aug 30, 2025
Completion
Aug 30, 2025
Last update posted
Mar 18, 2026

2022 – 2025

United States locations

U.S. sites
26
U.S. states
17
U.S. cities
21
Facility City State ZIP Site status
University of California, San Diego San Diego California 92037
South Lake Pain Institute Clermont Florida 34711
SIMEDHealth LLC Gainesville Florida 32607
University of Florida Gainesville Florida 32611
Northwestern Department of Neurology Chicago Illinois 60611
Healthcare Research Network (Flossmoor) Flossmoor Illinois 60422
University of Kansas Medical Center Kansas City Kansas 66160
University of Maryland - Baltimore Baltimore Maryland 21201
Johns Hopkins University School of Medicine Baltimore Maryland 21205
MGH Department of Anesthesia, Critical Care, and Pain Boston Massachusetts 02114
Healthcare Research Network (Hazelwood) Hazelwood Missouri 63042
NYU Langone Manhattan New York New York 10017
Mount Sinai School of Medicine New York New York 10029
Columbia University Medical Center/Neurological Institute New York New York 10032
University of Rochester Rochester New York 14627
Clinical Inquest Center Beavercreek Ohio 45431
University of Pittsburgh Pittsburgh Pennsylvania 15260
Low Country Pain Center Orangeburg South Carolina 29118
American Indian Clinical Trials Research Network Rapid City South Dakota 57701
Nerve and Muscle Center of Texas Houston Texas 77030
Clinicore International Houston Texas 77077
University of Utah School of Medicine Salt Lake City Utah 84132
Eastern Virginia Medical School Norfolk Virginia 23510
VCU Department of Neurology Richmond Virginia 23298
University of Washington Seattle Washington 98195
University of Wisconsin Madison Wisconsin 53706

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05480228, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 18, 2026 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05480228 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →