ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study
Public ClinicalTrials.gov record NCT05481827. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT05481827
- Recruitment status
- Enrolling by invitation
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Gyroscope Therapeutics Limited
- Industry
- Enrollment
- 225 participants
Conditions and interventions
Conditions
Interventions
- GT005 Genetic
Genetic
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 11, 2022
- Primary completion
- Jun 1, 2028
- Completion
- Jun 1, 2028
- Last update posted
- Mar 21, 2024
2022 – 2028
United States locations
- U.S. sites
- 22
- U.S. states
- 15
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Consultants San Diego - Poway | Poway | California | 92064 | — |
| Southwest Retina Research Center | Durango | Colorado | 81303 | — |
| Vitreo Retinal Associates Pa - the Millennium Center Location | Gainesville | Florida | 32607-2557 | — |
| Rand Eye Institute, Inc. (Rei) | Pompano Beach | Florida | 33064 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| University Retina and Macula Associates, P.C. - Lemont Office | Lemont | Illinois | 60439-7421 | — |
| Midwest Eye Institute Northside | Indianapolis | Indiana | 46290 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| The Retina Care Center, Llc - Baltimore Location | Baltimore | Maryland | 21209 | — |
| Ophthalmic Consultants of Boston (OCB) | Boston | Massachusetts | 02114 | — |
| Pepose Vision Institute, P.C - Midwest Vision Research Foundation | Chesterfield | Missouri | 63017 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Retina Associates of Western New York | Rochester | New York | 14620 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Sterling Vision - Oregon Retina, Llp | Eugene | Oregon | 97401-2127 | — |
| Mid Atlantic Retina - Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Retina Consultants of Austin | Austin | Texas | 78705 | — |
| Texas Retina Associates (Tra) - Dallas Main | Dallas | Texas | 75231 | — |
| Retina Consultants of Texas (Retina Consultants of Houston) - Texas Medical Center | Houston | Texas | 77030-2727 | — |
| Retina Consultants of Texas (Retina Consultants of Houston) - Texas Medical Center | Houston | Texas | 77030 | — |
| Retinal Consultants of San Antonio (Rcsa) - Medical Center | San Antonio | Texas | 78240 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05481827, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 21, 2024 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05481827 live on ClinicalTrials.gov.