A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight
Public ClinicalTrials.gov record NCT05486065. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Investigation of Once-weekly Semaglutide S.C. Dose-Response in Patients With Type 2 Diabetes and Overweight - a Participant- and Investigator-blinded and Sponsor Open-label Study
Study identification
- NCT ID
- NCT05486065
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 245 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Semaglutide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 7, 2022
- Primary completion
- Oct 11, 2023
- Completion
- Dec 12, 2023
- Last update posted
- Dec 11, 2025
2022 – 2023
United States locations
- U.S. sites
- 101
- U.S. states
- 28
- U.S. cities
- 86
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama Birmingham | Birmingham | Alabama | 35294 | — |
| University of Alabama Birmingham | Birmingham | Alabama | 35294 | — |
| Velocity Clinical Res-Banning | Banning | California | 92220 | — |
| Velocity Clin Res-Chula Vista | Chula Vista | California | 91911 | — |
| Southern California Res Ctr | Coronado | California | 92118 | — |
| Cedars-Sinai Medical Group | Encino | California | 91436 | — |
| Velocity Clin Res Gardena | Gardena | California | 90247 | — |
| Nat Res Inst Huntington Park | Huntington Park | California | 90255 | — |
| Scripps Whittier Diabetes Inst | La Jolla | California | 92037 | — |
| First Valley Med Grp Lancaster | Lancaster | California | 93534 | — |
| Velocity Clin Res Los Angeles | Los Angeles | California | 90017 | — |
| Diabetes Assoc. Med Group | Orange | California | 92868 | — |
| Western University of Health Sciences | Pomona | California | 91766 | — |
| San Diego Family Care_San Diego | San Diego | California | 92111 | — |
| Mills-Peninsula Hlth Services | San Mateo | California | 94401 | — |
| Encompass Clinical Research_Spring Valley | Spring Valley | California | 91978 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Optumcare Clinical Trials,LLC-Golden | Colorado Springs | Colorado | 80906 | — |
| Innovative Research of W FL | Clearwater | Florida | 33756 | — |
| Tampa Bay Medical Research | Clearwater | Florida | 33761 | — |
| Alliance for Multispec Res | Coral Gables | Florida | 33134 | — |
| University Clin Res-Deland | DeLand | Florida | 32720 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Indago Research & Health Center Inc. | Hialeah | Florida | 33012 | — |
| Northeast Res Inst. Inc. | Jacksonville | Florida | 32204 | — |
| New Life Medical | Miami | Florida | 33130 | — |
| Genesis Research Center, LLC | Miami | Florida | 33155 | — |
| Suncoast Clinical Research, Inc. | Miami | Florida | 33173 | — |
| Reyes Clinical Research, Inc | Miami | Florida | 33174 | — |
| San Marcus Res Clin Miami Lakes | Miami Lakes | Florida | 33014 | — |
| Clinical Neuroscience Solution | Orlando | Florida | 32801 | — |
| Oviedo Medical Research, LLC | Oviedo | Florida | 32765 | — |
| Family Clinical Trials | Pembroke Pines | Florida | 33026 | — |
| Northeast Research Institute | Saint Augustine | Florida | 32080 | — |
| St Johns Center for Clin. Res | Saint Augustine | Florida | 32086 | — |
| Appalachian Clinical Res LLC | Adairsville | Georgia | 30103 | — |
| Urban Family Practice Assoc | Marietta | Georgia | 30067 | — |
| Herman Clinical Research LLC | Suwanee | Georgia | 30024 | — |
| Rocky Mt Clin Res, LLC | Idaho Falls | Idaho | 83404-7596 | — |
| Velocity Clinical Res Boise | Meridian | Idaho | 83642 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Biofortis Clinical Research | Addison | Illinois | 60101 | — |
| Cedar-Crosse Research Center | Chicago | Illinois | 60607 | — |
| West Broadway Clinic | Council Bluffs | Iowa | 51501 | — |
| Iowa Diab & Endo Res Center | West Des Moines | Iowa | 50266 | — |
| Cotton O'Neil Diab & Endo Ctr | Topeka | Kansas | 66606 | — |
| The Research Group of Lexington LLC | Lexington | Kentucky | 40503 | — |
| Norton Healthcare Research Office | Louisville | Kentucky | 40218 | — |
| Barnum Medical Research Inc. | Natchitoches | Louisiana | 71457 | — |
| MedStar Community Clin Res Ctr | Hyattsville | Maryland | 20782 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Endo And Metab Cons | Rockville | Maryland | 20852 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115-5804 | — |
| Aa Mrc Llc | Flint | Michigan | 48504 | — |
| Elite Research Center | Flint | Michigan | 48532 | — |
| Arcturus HC PLC Troy Med Res | Troy | Michigan | 48098 | — |
| Arcturus Healthcare, PLC | Troy | Michigan | 48098 | — |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | — |
| Premier Research Inc. | Trenton | New Jersey | 08611 | — |
| AMC Community Endocrinology | Albany | New York | 12203 | — |
| Mid Hudson Med Res-New Windsor | New Windsor | New York | 12553 | — |
| Northport VA Med Ctr Northport | Northport | New York | 11768 | — |
| Southgate Medical Group, LLP | West Seneca | New York | 14224 | — |
| UNC Eastowne Clinical Research Unit | Chapel Hill | North Carolina | 27514 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| Providence Health Partners Ctr | Dayton | Ohio | 45439 | — |
| Advanced Med Res Maumee | Maumee | Ohio | 43537 | — |
| Velocity Clin Res Grants Pass | Grants Pass | Oregon | 97527 | — |
| Velocity Clinical Res Medford | Medford | Oregon | 97504 | — |
| Lycoming Internal Medicine, Inc. | Jersey Shore | Pennsylvania | 17740 | — |
| Thomas Jefferson Univ Di Rsrch Ctr | Philadelphia | Pennsylvania | 19107 | — |
| Clinical Research of Philadelphia | Philadelphia | Pennsylvania | 19114 | — |
| CORE - Temple University | Philadelphia | Pennsylvania | 19140 | — |
| Tower Health | West Reading | Pennsylvania | 19611 | — |
| Velocity Clinical Research Columbia | Columbia | South Carolina | 29204 | — |
| Velocity Clinical Research Greenville | Greenville | South Carolina | 29615 | — |
| Coastal Carolina Res Ctr | Mt. Pleasant | South Carolina | 29464 | — |
| Trial Management Associates | Myrtle Beach | South Carolina | 29572 | — |
| Palmetto Clinical Research | Summerville | South Carolina | 29485 | — |
| Velocity Clinical Research Union | Union | South Carolina | 29379 | — |
| Chattanooga Medical Research, LLC | Chattanooga | Tennessee | 37404 | — |
| Murphy Research Center | Humboldt | Tennessee | 38343 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Clinical Neuroscience Solutions | Memphis | Tennessee | 38119 | — |
| Amarillo Med Spec LLP | Amarillo | Texas | 79106 | — |
| Velocity Clinical Res-Dallas | Dallas | Texas | 75230 | — |
| UT Southwestern Med Cntr | Dallas | Texas | 75390-9302 | — |
| Quality Research Inc | San Antonio | Texas | 78209 | — |
| Briggs Clinical Research, LLC | San Antonio | Texas | 78224 | — |
| VIP Trials | San Antonio | Texas | 78230 | — |
| DCT-Stone Oak | San Antonio | Texas | 78258 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Dwayne O. Williams, M.D., P.A. | Sugar Land | Texas | 77479 | — |
| Hillcrest Family Health Center | Waco | Texas | 76708 | — |
| Nova Health Management & Research Group, PC | Herndon | Virginia | 20171 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Amherst Family Practice P.C. | Winchester | Virginia | 22601 | — |
| Velocity Clinical Research Spokane | Spokane | Washington | 99203 | — |
| St. Vincent Hosp-Prevea Health | Green Bay | Wisconsin | 54303 | — |
| Clinical Investigation Spec. Kenosha | Kenosha | Wisconsin | 53144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05486065, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 11, 2025 · Synced May 13, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05486065 live on ClinicalTrials.gov.