Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males with Klinefelter Syndrome

ClinicalTrials.gov ID: NCT05498090

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Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will learn more about how the body uses energy. Usually, the body uses sugars as energy first and then fats are used when the sugar stores are gone. Some people have trouble using fats as energy. This can lead to feeling tired, difficulty exercising, and storing too much fat where it does not belong (like in the muscle). It is believed that some boys and men with Klinefelter Syndrome may not be able to use fats as energy normally, and that a medication called fenofibrate could help this.

Study identification

NCT ID: NCT05498090
Recruitment status: Not listed
Study type: Interventional
Phase: Phase 4
Lead sponsor: University of Colorado, Denver; Other
Enrollment: 44 participants

Conditions and interventions

Conditions

Klinefelter Syndrome

Interventions

Fenofibrate 145 mg Drug

Drug

Eligibility (public fields only)

Age range: 15 Years to 40 Years
Sex: Male
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 3, 2022 (Actual)
Primary completion: Jun 30, 2025 (Estimated)
Completion: Aug 30, 2025 (Estimated)
Last update posted: Oct 16, 2024

2022 – 2025

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Colorado - Anschutz Medical Campus	Aurora	Colorado	80045	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05498090, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 16, 2024 · Synced Nov 13, 2026