Safety and Immunogenicity of Three V181 Dengue Vaccine Potencies in Adults (V181-003)
Public ClinicalTrials.gov record NCT05507450. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Immunogenicity of Three Different Potency Levels of V181 (Dengue Quadrivalent Vaccine rDENVΔ30 [Live, Attenuated]) in Healthy Adults
Study identification
- NCT ID
- NCT05507450
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 1,271 participants
Conditions and interventions
Conditions
Interventions
- V181 High-Potency Level Biological
- V181 Mid-Potency Level Biological
- V181 Low-Potency Level Biological
- Placebo Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 6, 2022
- Primary completion
- Jun 4, 2023
- Completion
- May 6, 2024
- Last update posted
- May 8, 2025
2022 – 2024
United States locations
- U.S. sites
- 6
- U.S. states
- 5
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Research Foundation ( Site 0114) | San Diego | California | 92123 | — |
| Advanced Medical Research Institute ( Site 0115) | Miami | Florida | 33174 | — |
| Rochester Clinical Research, Inc. ( Site 0122) | Rochester | New York | 14609 | — |
| University of Texas Medical Branch ( Site 0113) | Galveston | Texas | 77555 | — |
| IMA Clinical Research San Antonio ( Site 0111) | San Antonio | Texas | 78229 | — |
| Alliance for Multispecialty Research LLC (AMR - Norfolk) ( Site 0123) | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05507450, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 8, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05507450 live on ClinicalTrials.gov.