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Active, not recruiting Phase 2 Interventional

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

ClinicalTrials.gov ID: NCT05509023

Public ClinicalTrials.gov record NCT05509023. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 7:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Phase 2a Proof-of-Concept Study Evaluating the Safety and Efficacy of ADX-914 in Subjects With Moderate to Severe Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a phase IIa, randomized, double-blind, placebo-controlled, multi-center proof-of-concept (POC) study in subjects with moderate to severe Atopic Dermatitis.

Study identification

NCT ID
NCT05509023
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Q32 Bio Inc.
Industry
Enrollment
102 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2022 (Actual)
Primary completion
Dec 2024 (Estimated)
Completion
Dec 2024 (Estimated)
Last update posted
Oct 3, 2024

2022 – 2024

United States locations

U.S. sites
24
U.S. states
14
U.S. cities
23
Facility City State ZIP Site status
Cahaba Dermatology Skin Health Center Birmingham Alabama 35244 —
First OC Dermatology Fountain Valley California 92708 —
California Allergy and Asthma Medical Group- Los Angeles Los Angeles California 90025 —
Integrative Skin Science and Research Sacramento California 95815 —
Dermatology Institute and Skin Care Center Santa Monica California 90404 —
Torrance Clinical Research Institute Inc. Torrance California 90505 —
Integrated Research of Inland, Inc. Upland California 91786 —
RM Medical Research Inc. Homestead Florida 33175 —
Medical Research Center of Miami Miami Florida 33134 —
Well Pharma Medical Research Corporation Miami Florida 33173 —
GCP Research St. Petersburg Florida 33705 —
Advanced Medical Research, PC Sandy Springs Georgia 30328 —
Treasure Valley Medical Research Boise Idaho 83706 —
Sneeze wheeze and Itch Associates LLC Normal Illinois 61761 —
Southern Indiana Clinical Trials New Albany Indiana 47150 —
Visage Clinical Research Largo Maryland 20774 —
Revival Research Corporation- Clinedge Troy Michigan 48084 —
Apex Clinical Research Center Painesville Ohio 33612 —
Clinical Partners, LLC Johnston Rhode Island 02919 —
North Texas Center for Clinical Research Frisco Texas 75034 —
Progressive Clinical Research San Antonio Texas 78213 —
JBR Clinical Research Salt Lake City Utah 84107 —
Dermatology of Seattle & Bellevue Seattle Washington 98004 —
Dermatology Specialists of Spokane Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05509023, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 3, 2024 · Synced Oct 16, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05509023 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →