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Terminated Phase 2 Interventional Results available

A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis

ClinicalTrials.gov ID: NCT05516758

Public ClinicalTrials.gov record NCT05516758. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 30, 2026, 12:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Double-Blind, Placebo-Controlled Study to Evaluate Peresolimab in Adult Participants With Moderately-to-Severely Active Rheumatoid Arthritis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to assess the safety and efficacy of peresolimab in adult participants with moderately-to-severely active rheumatoid arthritis.

Study identification

NCT ID
NCT05516758
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
491 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2022 (Actual)
Primary completion
Nov 20, 2023 (Actual)
Completion
Jan 17, 2025 (Actual)
Last update posted
Dec 4, 2025

2022 – 2025

United States locations

U.S. sites
54
U.S. states
20
U.S. cities
46
Facility City State ZIP Site status
Accel Research Sites - Birmingham Clinical Research Unit Birmingham Alabama 35216 —
Arizona Arthritis & Rheumatology Research PLLC Gilbert Arizona 85297 —
Arizona Arthritis & Rheumatology Research, PLLC Glendale Arizona 85306 —
Arizona Arthritis & Rheumatology Research, PLLC Mesa Arizona 85210 —
Arizona Arthritis & Rheumatology Associates, PLLC Phoenix Arizona 85037 —
Medvin Clinical Research - Metyas Covina California 91722 —
St Joseph Heritage Healthcare Fullerton California 92835 —
Newport Huntington Medical Group Huntington Beach California 92648 —
Desert Medical Advances Rancho Mirage California 92270 —
Dan La, MD Inc Tujunga California 91042 —
Wolverine Clinical Trials Tustin California 92780 —
Medvin Clinical Research - Su Whittier California 90602 —
Denver Arthritis Clinic Denver Colorado 80230 —
Tekton Research - Fort Collins - East Harmony Road Fort Collins Colorado 80528 —
HARAC Research Corp Avon Park Florida 33825 —
Encore Medical Research of Boynton Beach Boynton Beach Florida 33436 —
Clinical Research of West Florida, Inc. (Clearwater) Clearwater Florida 33765 —
Suncoast Clinical Research, Inc. New Port Richey Florida 34652 —
Baycare Medical Group St. Petersburg Florida 33705 —
West Broward Rheumatology Associates Tamarac Florida 33321 —
Clinical Research of West Florida Tampa Florida 33606 —
ForCare Clinical Research Tampa Florida 33613 —
Baycare Medical Group Tampa Florida 33614 —
Great Lakes Clinical Trials - Ravenswood Chicago Illinois 60640 —
Hinsdale Orthopaedics - llinois Bone & Joint Institute Hinsdale Illinois 60521 —
Accurate Clinical Research Lake Charles Louisiana 70605 —
Great Lakes Research Group, Inc. Bay City Michigan 48706 —
AA Medical Research Center Grand Blanc Michigan 48439 —
Arthritis and Rheumatology Center of MI - Rochester Hills Rochester Hills Michigan 48307 —
Clinvest Research LLC Springfield Missouri 65807 —
Saint Louis Rheumatology St Louis Missouri 63119 —
Arthritis & Osteoporosis Associates - Freehold Freehold New Jersey 07728 —
Albuquerque Center for Rheumatology Albuquerque New Mexico 87102 —
Albuquerque Clinical Trials, Inc. Albuquerque New Mexico 87102 —
Joseph S. and Diane H. Steinberg Ambulatory Care Center Brooklyn New York 11201 —
DJL Clinical Research, PLLC Charlotte North Carolina 28211 —
Cape Fear Arthritis Care Leland North Carolina 28451 —
Paramount Medical Research & Consulting, LLC Middleburg Heights Ohio 44130 —
Health Research of Oklahoma Oklahoma City Oklahoma 73103 —
Altoona Center For Clinical Research Duncansville Pennsylvania 16635 —
Piedmont Arthritis Clinic Greenville South Carolina 29601 —
Tekton Research, Inc Austin Texas 78745 —
Accurate Clinical Management Baytown Texas 77521 —
Metroplex Clinical Research Center Dallas Texas 75231 —
Biopharma Informatic, LLC Houston Texas 77043 —
Accurate Clinical Management - Houston Houston Texas 77084 —
Biopharma Informatic, LLC Houston Texas 77084 —
Accurate Clinical Research Houston Texas 77089 —
Laila A Hassan, MD, PA Houston Texas 77089 —
DM Clinical Research - Tomball Tomball Texas 77375 —
DM Clinical Research/Rheumatology Clinic of Houston Tomball Texas 77377 —
Sound Clinical Research, LLC Bothell Washington 98021 —
Arthritis Northwest, PLLC Spokane Washington 99204 —
Rheumatology & Pulmonary Clinic Beckley West Virginia 25801 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05516758, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 4, 2025 · Synced Oct 30, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05516758 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →