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Completed Phase 2 Interventional

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

ClinicalTrials.gov ID: NCT05551273

Public ClinicalTrials.gov record NCT05551273. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 11:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

Study identification

NCT ID
NCT05551273
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
29 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Selgantolimod Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 4, 2023
Primary completion
Oct 28, 2025
Completion
Apr 7, 2026
Last update posted
Apr 20, 2026

2023 – 2026

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Alabama CRS Birmingham Alabama 35222
UCSD Antiviral Research Center CRS San Diego California 92103
The Ponce de Leon Center CRS Atlanta Georgia 30308
Northwestern University CRS Chicago Illinois 60611
Weill Cornell Chelsea CRS New York New York 10011
Columbia P&S CRS New York New York 10032-3732
Weill Cornell Uptown CRS New York New York 10065
Chapel Hill CRS Chapel Hill North Carolina 27599
Greensboro CRS Site# 3203 Greensboro North Carolina 27401
Cincinnati Children's Hosp / Univ Hosp Cincinnati Ohio 452292899
Case CRS Site ID# 2501 Cleveland Ohio 44106
Ohio State University CRS Columbus Ohio 43210
Univ of Pittsburgh Pittsburgh Pennsylvania 15213
Vanderbilt Therapeutics (VT) CRS Nashville Tennessee 37204
Houston AIDS Research Team CRS Houston Texas 77030
University of Washington AIDS CRS Seattle Washington 98104-9929

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05551273, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 20, 2026 · Synced May 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05551273 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →