Gla-300 and IDeg-100 in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment
Public ClinicalTrials.gov record NCT05552859. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 24-Week, Multicenter, Randomized, Open-Label, Parallel-Group Trial Comparing the Efficacy and Safety of Insulin Glargine 300 U/mL (Gla-300) and Insulin Degludec 100 U/mL (IDeg-100) in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment: TRENT Trial
Study identification
- NCT ID
- NCT05552859
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 62 participants
Conditions and interventions
Conditions
Interventions
- Insulin degludec 100 U/mL Drug
- Insulin glargine 300 U/mL Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 4, 2022
- Primary completion
- Jul 27, 2023
- Completion
- Aug 3, 2023
- Last update posted
- Sep 7, 2025
2022 – 2023
United States locations
- U.S. sites
- 32
- U.S. states
- 14
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Yuma Clinical Trials, LLC Site Number: 8400028 | Yuma | Arizona | 85364-7110 | — |
| American Clinical Trials Site Number: 8400014 | Buena Park | California | 90620-3800 | — |
| Clearview Medical Research LLC Site Number: 8400021 | Canyon Country | California | 91351-4138 | — |
| Torrance Clinical Research Institute Site Number: 8400003 | Lomita | California | 90717-2101 | — |
| Center for Endocrinology Diabetes and Metabolic Disorders (CEDMD) - CAR Site Number: 8400026 | Santa Clarita | California | 91321-2454 | — |
| San Fernando Valley Health Institute - ClinEdge - PPDS Site Number: 8400023 | Van Nuys | California | 91405-3605 | — |
| Chase Medical Research LLC Site Number: 8400007 | Waterbury | Connecticut | 06708 | — |
| Innovative Research of West Florida Site Number: 8400016 | Clearwater | Florida | 33756-2004 | — |
| Evolution Clinical Trials Site number: 8400034 | Hialeah Gardens | Florida | 33016 | — |
| Wellness Research Center Inc - Miami Site Number: 8400010 | Miami | Florida | 33135-1601 | — |
| Med Research of Florida, LLC Investigator Site: 8400033 | Miami | Florida | 33186 | — |
| Florida Institute For Clinical Research LLC Site Number: 8400004 | Orlando | Florida | 32825 | — |
| Emory University Site Number: 8400032 | Atlanta | Georgia | 30303 | — |
| Agile Clinical Research Trials, LLC Site Number: 8400001 | Atlanta | Georgia | 30328-5532 | — |
| Centricity Research Site Number: 8400006 | Columbus | Georgia | 31904 | — |
| Georgia Clinical Research Site Number: 8400009 | Lawrenceville | Georgia | 30044-5896 | — |
| Endocrine and Metabolic Consultants Research Center Site Number: 8400031 | Rockville | Maryland | 20852 | — |
| Diabetes, Obesity, Cardiovascular Clinical Specialists (DOCS) Site Number: 8400019 | Las Vegas | Nevada | 89113-3628 | — |
| Mid Hudson Medical Research PLLC Site Number: 8400024 | New Windsor | New York | 12553-7754 | — |
| Lucas Research - Morehead City - HyperCore - PPDS Site Number: 8400008 | Morehead City | North Carolina | 28557-3126 | — |
| Advanced Medical Research Site Number: 8400012 | Maumee | Ohio | 43537-1863 | — |
| Capital Area Research LLC Site Number: 8400029 | Newport | Pennsylvania | 17074 | — |
| Jefferson University Physicians (JUP) Site Number: 8400025 | Philadelphia | Pennsylvania | 19107-6810 | — |
| Holston Medical Group PC Site Number: 8400018 | Bristol | Tennessee | 37620-7353 | — |
| Frontier Medical Center Site Number: 8400035 | El Paso | Texas | 79935-4202 | — |
| Diabetes and Thyroid Center of Fort Worth PLLC Site Number: 8400015 | Fort Worth | Texas | 76132-4242 | — |
| Juno Research, LLC Site Number: 8400017 | Houston | Texas | 77054 | — |
| Reichman and Associates Site Number: 8400013 | Houston | Texas | 77074-1691 | — |
| Texas Institute for Kidney and Endocrine Disorders Site Number: 8400027 | Lufkin | Texas | 75904-3163 | — |
| Northeast Clinical Research of San Antonio LLC Site Number: 8400022 | Schertz | Texas | 78154-1403 | — |
| Consano Clinical Research Site Number: 8400030 | Shavano Park | Texas | 78231 | — |
| David Ramstad Associates Research - IACT - HyperCore - PPDS Site Number: 8400005 | Suffolk | Virginia | 23435-3763 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05552859, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 7, 2025 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05552859 live on ClinicalTrials.gov.