Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
Public ClinicalTrials.gov record NCT05553366. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
Study identification
- NCT ID
- NCT05553366
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Enrollment
- 1,075 participants
Conditions and interventions
Conditions
Interventions
- SUZ Drug
- HB/APAP Drug
- Placebo (matched to SUZ) Drug
- Placebo (matched to HB/APAP) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2, 2022
- Primary completion
- Dec 14, 2023
- Completion
- Dec 14, 2023
- Last update posted
- Jul 31, 2025
2022 – 2023
United States locations
- U.S. sites
- 21
- U.S. states
- 11
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Shoals Medical Trials Inc. | Sheffield | Alabama | 35660 | — |
| Arizona Research Center | Phoenix | Arizona | 85053 | — |
| Woodland International Research Group | Little Rock | Arkansas | 72211 | — |
| Anaheim Clinical Trials | Anaheim | California | 92801 | — |
| Trovare Clinical Research | Bakersfield | California | 93301 | — |
| Pacific Research Network Inc | San Diego | California | 92103 | — |
| New Hope Research Development | Tarzana | California | 91356 | — |
| New Hope Research Development | West Covina | California | 91790 | — |
| Clinical Pharmacology of Miami | Hialeah | Florida | 33014 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Kansas Spine and Specialty Hospital | Wichita | Kansas | 67226 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45417 | — |
| Center for Orthopaedic Reconstruction and Excellence | Jenks | Oklahoma | 74037 | — |
| HD Research LLC | First Surgical Hospital | Bellaire | Texas | 77401 | — |
| HD Research LLC | Legent Orthopedic Hospital | Carrollton | Texas | 75006 | — |
| HD Research LLC | Houston Heights Hospital | Houston | Texas | 77008 | — |
| Futuro Clinical Trials | McAllen | Texas | 78501 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Houston Physicians Hospital | Webster | Texas | 77598 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05553366, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 31, 2025 · Synced Jun 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05553366 live on ClinicalTrials.gov.