ClinicalTrials.gov record
A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity
ClinicalTrials.gov ID: NCT05556512
Public ClinicalTrials.gov record NCT05556512. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-Controlled Study to Investigate the Effect of Tirzepatide on the Reduction of Morbidity and Mortality in Adults With Obesity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additional evidence for the potential clinical benefits of tirzepatide in this population.
Study identification
- NCT ID
- NCT05556512
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 15,374 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 10, 2022
- Primary completion
- Sep 30, 2027
- Completion
- Sep 30, 2027
- Last update posted
- Sep 21, 2026
2022 – 2027
United States locations
- U.S. sites
- 165
- U.S. states
- 38
- U.S. cities
- 144
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC | Gilbert | Arizona | 85296 | — |
| Aventiv Research | Mesa | Arizona | 85206 | — |
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| Pima Heart | Tucson | Arizona | 85741 | — |
| KLR Business Group, Inc. dba Arkansas Clinical Research | Little Rock | Arkansas | 72205 | — |
| Smart Cures Clinical Research | Anaheim | California | 92806 | — |
| Trident Clinical Research Services, Inc. | Apple Valley | California | 92307 | — |
| Hope Clinical Research, Inc. | Canoga Park | California | 91303 | — |
| John Muir Physician Network Research Center | Concord | California | 94520 | — |
| Neighborhood Healthcare Institute of Health | Escondido | California | 92025 | — |
| HB Clinical Trials - Fountain Valley | Fountain Valley | California | 92708 | — |
| Valiance Clinical Research | Huntington Park | California | 90255 | — |
| Scripps Whittier Diabetes Institute | La Jolla | California | 92037 | — |
| Velocity Clinical Research, San Diego | La Mesa | California | 91942 | — |
| First Valley Medical Group | Lancaster | California | 93534 | — |
| Long Beach Clinical Trials | Long Beach | California | 90806 | — |
| Infinity Clinical Research - Norco | Norco | California | 92860 | — |
| California Medical Research Associates | Northridge | California | 91324 | — |
| Diabetes Associates Medical Group | Orange | California | 92868 | — |
| University of California Irvine Medical Center | Orange | California | 92868 | — |
| FOMAT Medical Research | Oxnard | California | 93030 | — |
| Desert Oasis Healthcare Medical Group | Palm Springs | California | 92262 | — |
| Dream Team Clinical Research | Pomona | California | 91767 | — |
| Rancho Cucamonga Clinical Research | Rancho Cucamonga | California | 91730 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92123 | — |
| Velocity Clinical Research, Santa Ana | Santa Ana | California | 92704 | — |
| Valiance Clinical Research | Tarzana | California | 91356 | — |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Millennium Clinical Trials | Westlake Village | California | 91361 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Optum- Southwestern | Colorado Springs | Colorado | 80906 | — |
| Kidney Associates of Colorado | Denver | Colorado | 80210 | — |
| OptumCare Clinical Trials, LLC | Golden | Colorado | 80401 | — |
| Clinical Research Consulting | Milford | Connecticut | 06460 | — |
| Cardiology Associates of Fairfield County, P.C. | Stamford | Connecticut | 06905 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials | Boca Raton | Florida | 33434 | — |
| Encore Medical Research of Boynton Beach | Boynton Beach | Florida | 33436 | — |
| Clinical Research of West Florida, Inc. (Clearwater) | Clearwater | Florida | 33765 | — |
| Northeast Research Institute (NERI) | Fleming Island | Florida | 32003 | — |
| Northeast Research Institute - Downtown Office | Jacksonville | Florida | 32204 | — |
| IHS Health Research | Kissimmee | Florida | 34741 | — |
| Clinical Research of Central Florida | Lakeland | Florida | 33805 | — |
| South Florida Clinical Research Institute | Margate | Florida | 33063 | — |
| Felicidad Medical Research | Miami | Florida | 33184 | — |
| Floridian Clinical Research, LLC | Miami Lakes | Florida | 33016-1518 | — |
| Indago Research & Health Center, Inc | Miami Lakes | Florida | 33016 | — |
| Florida Institute For Clinical Research, LLC | Orlando | Florida | 32825 | — |
| Peace River Cardiovascular Center | Port Charlotte | Florida | 33952 | — |
| Northeast Research Institute - St. Augustine | Saint Augustine | Florida | 32080 | — |
| IMA Clinical Research St. Petersburg | St. Petersburg | Florida | 33704 | — |
| Clinical Research of West Florida | Tampa | Florida | 33606 | — |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | — |
| Masters of Clinical Research | Augusta | Georgia | 30909 | — |
| HOPE Clinical Research & Wellness | Conyers | Georgia | 30094 | — |
| Center for Advanced Research & Education | Gainesville | Georgia | 30501 | — |
| NSC Research | Johns Creek | Georgia | 30024 | — |
| Balanced Life Health Care Solutions/SKYCRNG | Lawrenceville | Georgia | 30046 | — |
| WR-Mount Vernon Clinical Research, LLC | Sandy Springs | Georgia | 30328 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Elite Clinical Trials | Blackfoot | Idaho | 83221 | — |
| Rocky Mountain Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Velocity Clinical Research, Boise | Meridian | Idaho | 83642 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| IMA Clinical Research Chicago | Chicago | Illinois | 60634 | — |
| Central Illinois Diabetes and Clinical Research a Division of Prairie Education and Research Cooperative | Springfield | Illinois | 62711 | — |
| Healthcare Research Network - Chicago | Tinley Park | Illinois | 60477 | — |
| American Health Network of Indiana, LLC - Avon | Avon | Indiana | 46123 | — |
| Qualmedica Research, LLC | Evansville | Indiana | 47715 | — |
| American Health Network of Indiana, LLC - Greenfield | Greenfield | Indiana | 46140 | — |
| American Health Network of Indiana, LLC - Whiteland | Whiteland | Indiana | 46184 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50266 | — |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | 66606 | — |
| Cotton O'Neil Mulvane | Topeka | Kansas | 66606 | — |
| Qualmedica Research | Bowling Green | Kentucky | 42101 | — |
| Monroe Biomedical Research - Louisville | Louisville | Kentucky | 40213 | — |
| Qualmedica Research, LLC | Owensboro | Kentucky | 42301 | — |
| Ascension Saint Agnes Heart Care | Baltimore | Maryland | 21229 | — |
| Centennial Medical Group | Columbia | Maryland | 21045 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital Diabetes Program | Boston | Massachusetts | 02115 | — |
| NECCR PrimaCare Research | Fall River | Massachusetts | 02721 | — |
| ActivMed Practices and Research | Methuen | Massachusetts | 01844 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| M Health Fairview St. John's Hospital | Maplewood | Minnesota | 55109 | — |
| Memorial Hospital at Gulfport | Diamondhead | Mississippi | 39525 | — |
| Prime Health and Wellness/SKYCRNG | Fayette | Mississippi | 39069 | — |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654-3514 | — |
| SKY Integrative Medical Center/SKYCRNG | Ridgeland | Mississippi | 39157 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Healthcare Research Network - St. Louis | Hazelwood | Missouri | 63042 | — |
| Clinvest Research LLC | Springfield | Missouri | 65807 | — |
| IMA Clinical Research - St. Louis | St Louis | Missouri | 63117 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| VA Nebraska-Western Iowa Health Care System | Omaha | Nebraska | 68105 | — |
| DaVita Clinical Research - Las Vegas | Las Vegas | Nevada | 89107 | — |
| Excel Clinical Research, LLC | Las Vegas | Nevada | 89109 | — |
| Palm Research Center Tenaya | Las Vegas | Nevada | 89128 | — |
| Palm Research Center Sunset | Las Vegas | Nevada | 89148 | — |
| Advanced Research Institute - Reno | Reno | Nevada | 89511 | — |
| UniMed Center | East Brunswick | New Jersey | 08816 | — |
| NJ MedCare & NJ Heart | Linden | New Jersey | 07036 | — |
| Hassman Research Institute Marlton Site | Marlton | New Jersey | 08053 | — |
| IMA Clinical Research Warren | Warren Township | New Jersey | 07059 | — |
| IMA Clinical Research | Albuquerque | New Mexico | 87109 | — |
| Albany Medical College, Division of Community Endocrinology | Albany | New York | 12203 | — |
| Meridian Clinical Research, LLC | Binghamton | New York | 13905 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| IMA Clinical Research | New York | New York | 10036 | — |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | — |
| Meridian Clinical Research, LLC | Vestal | New York | 13850 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| Centricity Research Columbus Ohio Multispecialty | Columbus | Ohio | 43213 | — |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | — |
| The Corvallis Clinic, P.C. | Corvallis | Oregon | 97330 | — |
| Heritage Valley Medical Group, Inc. | Beaver | Pennsylvania | 15009 | — |
| Capital Area Research, LLC | Camp Hill | Pennsylvania | 17011 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Tristar Clinical Investigations | Philadelphia | Pennsylvania | 19114 | — |
| Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair | Pittsburgh | Pennsylvania | 15243 | — |
| Cardiology Consultants of Philadelphia Yardley | Yardley | Pennsylvania | 19067 | — |
| WR-Clinsearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78749 | — |
| Pinnacle Clinical Research | Austin | Texas | 78757 | — |
| Dallas Diabetes Research Center | Dallas | Texas | 75230 | — |
| Soma Clinical Trials | Denison | Texas | 75020 | — |
| Medresearch Inc | El Paso | Texas | 79902 | — |
| Diabetes and Thyroid Center of Ft. Worth | Fort Worth | Texas | 76132 | — |
| Valley Institute of Research - Fort Worth | Fort Worth | Texas | 76164 | — |
| AngioCardiac Care of Texas, PA | Houston | Texas | 77025 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Next Level Urgent Care | Houston | Texas | 77057 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77084 | — |
| Research Physicians Network, LLC | Houston | Texas | 77089 | — |
| Epic Clinical Research | Lewisville | Texas | 75057 | — |
| Texas Institute for Kidney and Endocrine Disorders | Lufkin | Texas | 75904 | — |
| Biopharma Informatic, LLC | McAllen | Texas | 78503 | — |
| Texas Institute of Cardiology, PA | McKinney | Texas | 75071 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| North Hills Family Medicine/North Hills Medical Research | North Richland Hills | Texas | 76180 | — |
| Clinical Trials of Texas, LLC | San Antonio | Texas | 78229 | — |
| Pinnacle Clinical Research | San Antonio | Texas | 78229 | — |
| VIP Trials | San Antonio | Texas | 78230 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| DaVita Clinical Research - North Houston | Shenandoah | Texas | 77384 | — |
| Northwest Houston Heart Center | Tomball | Texas | 77375 | — |
| Velocity Clinical Research, Waco | Waco | Texas | 76710 | — |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | — |
| Soma Clinical Trials | Wylie | Texas | 75098 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| Advanced Research Institute - Sandy | Sandy City | Utah | 84070 | — |
| Kalo Clinical Research | West Valley City | Utah | 84120 | — |
| Dominion Medical Associates, Inc. | Richmond | Virginia | 23219 | — |
| National Clinical Research, Inc | Richmond | Virginia | 23294 | — |
| Eastside Research Associates | Redmond | Washington | 98052 | — |
| Rainier Clinical Research Center | Renton | Washington | 98057 | — |
| Central Washington Health Services Association d/b/a Confluence Health | Wenatchee | Washington | 98801 | — |
| IMA Clinical Research | Morgantown | West Virginia | 26505 | — |
| St. Vincent Hospital d/b/a Prevea Health | Green Bay | Wisconsin | 54303 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 506 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05556512, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2026 · Synced Sep 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05556512 live on ClinicalTrials.gov.