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Completed Phase 3 Interventional Results available

A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With a Next-Generation Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

ClinicalTrials.gov ID: NCT05573464

Public ClinicalTrials.gov record NCT05573464. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, 12-Week (With an Extension to 52 Weeks in a Subset of Participants), Multi-Center Study to Assess the Safety of Budesonide, Glycopyrronium, and Formoterol Fumarate (BGF) Delivered by MDI HFO Compared to BGF Delivered by MDI HFA in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

Study identification

NCT ID
NCT05573464
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
559 participants

Conditions and interventions

Interventions

  • BGF MDI HFO 320/14.4/9.6 μg Drug
  • BGF MDI HFA 320/14.4/9.6 μg Drug

Drug

Eligibility (public fields only)

Age range
40 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 26, 2022
Primary completion
Mar 25, 2024
Completion
Mar 25, 2024
Last update posted
Sep 18, 2025

2022 – 2024

United States locations

U.S. sites
20
U.S. states
13
U.S. cities
20
Facility City State ZIP Site status
Research Site Phoenix Arizona 85032
Research Site Newport Beach California 92663
Research Site Miami Florida 33175
Research Site Sarasota Florida 34239
Research Site Tampa Florida 33606
Research Site Valparaiso Indiana 46383
Research Site Crowley Louisiana 70526
Research Site North Dartmouth Massachusetts 02747
Research Site St Louis Missouri 63141
Research Site Charlotte North Carolina 28209
Research Site Wilmington North Carolina 28401
Research Site Dublin Ohio 43016
Research Site Grants Pass Oregon 97527
Research Site Portland Oregon 97202
Research Site Anderson South Carolina 29621
Research Site Columbia South Carolina 29204
Research Site Gaffney South Carolina 29340
Research Site Longview Texas 75605
Research Site McKinney Texas 75069
Research Site Richmond Virginia 23219

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05573464, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 18, 2025 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05573464 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →