A Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age
Public ClinicalTrials.gov record NCT05575492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2a Open-Label Dose-Ranging and Observer-Blind Placebo-Controlled, Safety and Immunogenicity Study of mRNA-1647 Cytomegalovirus Vaccine in Female and Male Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of study is to evaluate the safety and immunogenicity of different dose levels of mRNA-1647 versus control in healthy cytomegalovirus (CMV)-seronegative and CMV-seropositive female and male participants 9 to 15 years of age. In addition, mRNA-1647 will be evaluated in female participants 16 to 25 years as a comparator cohort.
Study identification
- NCT ID
- NCT05575492
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 873 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 9 Years to 25 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 7, 2022 (Actual)
- Primary completion
- May 12, 2026 (Actual)
- Completion
- May 12, 2026 (Actual)
- Last update posted
- Jun 4, 2026
2022 – 2026
United States locations
- U.S. sites
- 44
- U.S. states
- 20
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Paradigm Clinical Research Institute Inc - ClinEdge - PPDS | La Mesa | California | 91942-3189 | — |
| Velocity Clinical Research - San Diego - PPDS | La Mesa | California | 91942 | — |
| Benchmark Research - Sacramento -Hypercore- PPDS | Sacramento | California | 95864 | — |
| Tekton Research - Fort Collins - Platinum - PPDS | Fort Collins | Colorado | 80525-5752 | — |
| Velocity Clinical Research (Washington)- PPDS | Washington D.C. | District of Columbia | 20016 | — |
| Prohealth Research Center | Doral | Florida | 33166-6613 | — |
| University of Florida Jacksonville | Jacksonville | Florida | 32209 | — |
| Clinical Neurosciences Solutions Inc. (Orlando-East South St) | Orlando | Florida | 32801-2987 | — |
| Palm Harbor Dermatology | Tampa | Florida | 33609-2230 | — |
| Santos Research Center | Tampa | Florida | 33615-3219 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30322-1014 | — |
| iResearch Atlanta - CenExel - PPDS | Decatur | Georgia | 30030-3438 | — |
| Clinical Research Prime - ClinEdge - PPDS | Idaho Falls | Idaho | 83404-5305 | — |
| Benchmark Research - Covington - HyperCore- PPDS | Covington | Louisiana | 70433 | — |
| Tulane Medical Center | New Orleans | Louisiana | 70112-2632 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201-1509 | — |
| The Pediatric Centre | Columbia | Maryland | 21045 | — |
| The Pediatric Centre of Frederick | Frederick | Maryland | 21702 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Velocity Clinical Research - Gulfport | Gulfport | Mississippi | 39503 | — |
| Velocity Clinical Research (Lincoln-Nebraska) - PPDS | Lincoln | Nebraska | 68510 | — |
| Velocity Clinical Research (Norfolk - Nebraska) - PPDS | Norfolk | Nebraska | 68701-7701 | — |
| Velocity Clinical Research (Omaha-Nebraska) - Platinum - PPDS | Omaha | Nebraska | 68134-3664 | — |
| Albuquerque Clinical Trials Inc - Clinedge - PPDS | Albuquerque | New Mexico | 87102-2619 | — |
| Velocity Clinical Research -Albuquerque -PPDS | Albuquerque | New Mexico | 87102-3644 | — |
| Velocity Clinical Research (Binghamton - New York) - PPDS | Binghamton | New York | 13901-1046 | — |
| Rochester Clinical Research, Inc | Rochester | New York | 14609-3173 | — |
| OnSite Clinical Solutions, LLC - ClinEdge - PPDS | Charlotte | North Carolina | 28277-4859 | — |
| Tekton Research - Oklahoma- PPDS | Edmond | Oklahoma | 73013 | — |
| Lynn Institute of Norman - ERN - PPDS | Norman | Oklahoma | 73072-3251 | — |
| Velocity Clinical Research - Medford - PPDS | Medford | Oregon | 97504-7738 | — |
| Meharry Medical College | Nashville | Tennessee | 37208 | — |
| Tekton Research - Texas - PPDS | Austin | Texas | 78705 | — |
| Tekton Research - Beaumont - Platinum - PPDS | Beaumont | Texas | 77706-3061 | — |
| Benchmark Research - Fort Worth - HyperCore -PPDS | Fort Worth | Texas | 76135 | — |
| University of Texas Medical Branch (UTMB) | Galveston | Texas | 77550 | — |
| West Houston Clinical Research - Hunt - PPDS | Houston | Texas | 77055-1626 | — |
| Victoria Clinical Research Group | Port Lavaca | Texas | 77979 | — |
| Benchmark Research - San Angelo - HyperCore - PPDS | San Angelo | Texas | 76904 | — |
| Tekton Research - Texas - Platinum - PPDS | San Antonio | Texas | 78229 | — |
| DM Clinical Research - ERN- PPDS | Tomball | Texas | 77375 | — |
| Crossroads Clinical Research (Victoria) | Victoria | Texas | 77901 | — |
| JBR Clinical Research - CenExel JBR - PPDS | Salt Lake City | Utah | 84107-4536 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05575492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05575492 live on ClinicalTrials.gov.