Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity
Public ClinicalTrials.gov record NCT05579977. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, DOSE RANGING, DOSE FINDING, PARALLEL GROUP STUDY TO ASSESS EFFICACY AND SAFETY OF PF-07081532, AND OPEN LABEL ORAL SEMAGLUTIDE, IN ADULTS WITH TYPE 2 DIABETES MELLITUS (T2DM) INADEQUATELY CONTROLLED ON METFORMIN, AND SEPARATELY PF-07081532 COMPARED TO MATCHING PLACEBO IN ADULTS WITH OBESITY BUT WITHOUT T2DM
Study identification
- NCT ID
- NCT05579977
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 902 participants
Conditions and interventions
Conditions
Interventions
- PF-07081532 Drug
- Placebo Other
- Rybelsus Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 26, 2022
- Primary completion
- Jul 13, 2023
- Completion
- Sep 21, 2023
- Last update posted
- Jul 31, 2024
2022 – 2023
United States locations
- U.S. sites
- 39
- U.S. states
- 19
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Trinity Clinical Research | Centreville | Alabama | 35042 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| San Fernando Valley Health Institute | Canoga Park | California | 91304 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Innovative Research of West Florida | Clearwater | Florida | 33756 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Adult Medicine of Lake County | Mt. Dora | Florida | 32757 | — |
| Endocrine Research Solutions, Inc. | Roswell | Georgia | 30076 | — |
| Cedar Crosse Research Center | Chicago | Illinois | 60607 | — |
| Evanston Premier Healthcare Research LLC | Skokie | Illinois | 60077 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50265 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Premier Research | Trenton | New Jersey | 08611 | — |
| Medication Management | Greensboro | North Carolina | 27405 | — |
| Meridian Clinical Research, LLC | Cincinnati | Ohio | 45219 | — |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | — |
| Heritage Valley Multispecialty Group, Inc | Beaver | Pennsylvania | 15009 | — |
| Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18) | Pittsburgh | Pennsylvania | 15236 | — |
| Preferred Primary Care Physicians | Uniontown | Pennsylvania | 15401 | — |
| Velocity Clinical Research, Providence | East Greenwich | Rhode Island | 02818 | — |
| HealthStar Physicians, P.C. | Morristown | Tennessee | 37813 | — |
| Healthstar Physicians | Morristown | Tennessee | 37813 | — |
| Elligo Clinical Research Center | Austin | Texas | 78738 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Medical Colleagues of Texas, LLP | Katy | Texas | 77450 | — |
| Tapia Internal Medicine Clinic | Paris | Texas | 75462 | — |
| Northeast Clinical Research of San Antonio | San Antonio | Texas | 78233 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Sugar Lakes Family Practice | Sugar Land | Texas | 77479 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| Southwest Internal Medicine | St. George | Utah | 84790 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 51 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05579977, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 31, 2024 · Synced May 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05579977 live on ClinicalTrials.gov.