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Completed Phase 3 Interventional

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

ClinicalTrials.gov ID: NCT05582395

Public ClinicalTrials.gov record NCT05582395. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Clinical Study to Evaluate Mavacamten in Adults With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Study identification

NCT ID
NCT05582395
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
580 participants

Conditions and interventions

Interventions

  • Mavacamten Drug
  • Placebo Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 13, 2022
Primary completion
Mar 5, 2025
Completion
Oct 19, 2025
Last update posted
Nov 13, 2025

2022 – 2025

United States locations

U.S. sites
41
U.S. states
24
U.S. cities
39
Facility City State ZIP Site status
Local Institution - 0082 Birmingham Alabama 35233-1900
Local Institution - 0458 Phoenix Arizona 85054
Local Institution - 0409 La Jolla California 92037-1337
Local Institution - 0010 Los Angeles California 90048-3311
Local Institution - 0406 San Francisco California 94143-2204
Local Institution - 0079 Stanford California 94305-2200
Local Institution - 0468 Gainesville Florida 32608-1134
Local Institution - 0281 Tampa Florida 33606-3603
Local Institution - 0092 Atlanta Georgia 30322
Local Institution - 0424 Indianapolis Indiana 46202-1243
Local Institution - 0070 Iowa City Iowa 52242-1009
Local Institution - 0410 Kansas City Kansas 66160-8500
Local Institution - 0484 Louisville Kentucky 40217-1363
Local Institution - 0127 Baltimore Maryland 21287
Local Institution - 0479 Boston Massachusetts 02114
Local Institution - 0500 Boston Massachusetts 02118-2908
Local Institution - 0464 Ann Arbor Michigan 48109
Local Institution - 0064 Detroit Michigan 48202-2608
Local Institution - 0455 Grand Rapids Michigan 49525
Local Institution - 0431 Rochester Minnesota 55905
Local Institution - 0461 St Louis Missouri 63110
Local Institution - 0435 Omaha Nebraska 68198-2265
Local Institution - 0490 Morristown New Jersey 07962
Local Institution - 0449 Manhasset New York 11030-3816
Local Institution - 0486 New York New York 10019-1147
Local Institution - 0007 Stony Brook New York 11790-3407
Local Institution - 0426 Valhalla New York 10595
Local Institution - 0094 Charlotte North Carolina 28204-2826
Local Institution - 0065 Durham North Carolina 27710
Local Institution - 0083 Cleveland Ohio 44195
Local Institution - 0047 Hershey Pennsylvania 17033
Local Institution - 0444 Lancaster Pennsylvania 17602-2250
Local Institution - 0263 Philadelphia Pennsylvania 19104
Local Institution - 0081 Pittsburgh Pennsylvania 15213-2536
Local Institution - 0207 Germantown Tennessee 38138-1727
Local Institution - 0089 Dallas Texas 75246
Local Institution - 0365 Dallas Texas 75390
Local Institution - 0492 Plano Texas 75093
Local Institution - 0402 Salt Lake City Utah 84132-0001
Local Institution - 0478 Charlottesville Virginia 22908-0001
Local Institution - 0095 Richmond Virginia 23298-5024

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 183 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05582395, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 13, 2025 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05582395 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →