ClinicalTrials.gov record
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov ID: NCT05595642
Public ClinicalTrials.gov record NCT05595642. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Astegolimab in Patients With Chronic Obstructive Pulmonary Disease
Study identification
- NCT ID
- NCT05595642
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 1,290 participants
Conditions and interventions
Conditions
Interventions
- Astegolimab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 28, 2022
- Primary completion
- Jun 23, 2025
- Completion
- Sep 23, 2027
- Last update posted
- May 19, 2026
2022 – 2027
United States locations
- U.S. sites
- 53
- U.S. states
- 25
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| SEC Clinical Research LLC - Dothan 2 - ClinEdge - PPDS | Dothan | Alabama | 36305 | — |
| Pulmonary Associates PA | Glendale | Arizona | 85306-4669 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Tucson | Tucson | Arizona | 85741-3118 | — |
| Kern Research | Bakersfield | California | 93301 | — |
| Allergy & Asthma Medical Group of the Bay Area | Walnut Creek | California | 94598 | — |
| Finlay Medical Research Corporation | Greenacres City | Florida | 33467-2979 | — |
| San Marcus Research Clinic Inc. | Miami | Florida | 33014 | — |
| Oceane7 Medical & Research Center, Inc. | Miami | Florida | 33144-2155 | — |
| Avantis Clinical Research, LLC | Miami | Florida | 33155-3265 | — |
| Research Institute of South Florida Inc | Miami | Florida | 33173 | — |
| Diverse Clinical Research, LLC | Miami | Florida | 33175-3434 | — |
| Central Florida Pulmonary Group, PA | Orlando | Florida | 32803 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - The Villages | The Villages | Florida | 32162-7116 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Atlanta | Atlanta | Georgia | 30328 | — |
| Allergy Center at Brookstone Research - Centricity Research - HyperCore - PPD | Columbus | Georgia | 31904-2954 | — |
| Pivotal Research Solutions | Stonecrest | Georgia | 30038-2649 | — |
| ASHA Clinical Research - ClinEdge - PPDS | Hammond | Indiana | 46324-2213 | — |
| The Research Group of Lexington, LLC | Lexington | Kentucky | 40504 | — |
| Best Clinical Trials | New Orleans | Louisiana | 70115 | — |
| Paul A. Shapero, MD, PA | Bangor | Maine | 04401-5691 | — |
| Pulmonary Research Institute of Southeast Michigan | Farmington Hills | Michigan | 48336-2817 | — |
| Flushing Road Internal Medicine and Pediatrics - F | Flint | Michigan | 48504-4730 | — |
| Revive Research Institute | Lathrup Village | Michigan | 48076 | — |
| Oakland Medical Research Center | Troy | Michigan | 48085-5524 | — |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63110 | — |
| Nebraska Medical Research Institute, Inc. - CRN | Bellevue | Nebraska | 68123-4318 | — |
| Machuca Family Medicine | Las Vegas | Nevada | 89104-3953 | — |
| Renown Regional Medical Center Hospital | Reno | Nevada | 89502-1576 | — |
| Hassman Research Institute - HRI - Berlin - CenExel - PPDS | Marlton | New Jersey | 08053 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - New York | New York | New York | 10017-4008 | — |
| Research Carolina Elite | Denver | North Carolina | 28037-7929 | — |
| Pulmonix LLC | Greensboro | North Carolina | 27403 | — |
| Advanced Respiratory and Sleep Medicine, PLLC | Huntersville | North Carolina | 28078 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103-4029 | — |
| OK Clinical Research | Edmond | Oklahoma | 73034-3258 | — |
| The Oregon Clinic | Portland | Oregon | 97213 | — |
| Clinical Research Associates Of Central Pa , Llc | Altoona | Pennsylvania | 16602 | — |
| Allergy & Clinical Immun Assoc | Pittsburgh | Pennsylvania | 15241 | — |
| Medtrial, LLC | Columbia | South Carolina | 29204 | — |
| Velocity Clinical Research - Gaffney - PPDS | Gaffney | South Carolina | 29340-4737 | — |
| ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Clinical Trials Center of Middle Tennessee | Franklin | Tennessee | 37067-5603 | — |
| Tennessee Comprehensive Lung & Sleep Center | Hendersonville | Tennessee | 37075-3085 | — |
| TTS Research | Boerne | Texas | 78006 | — |
| Corsicana Medical Research | Corsicana | Texas | 75110-2471 | — |
| Trio Clinical Trials | Houston | Texas | 77008 | — |
| Baylor College of Medicine Medical Center | Houston | Texas | 77030 | — |
| Biopharma Informatic - Park Row - PPDS | Houston | Texas | 77084 | — |
| R & H Clinical Research | Katy | Texas | 77494-2031 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Western Washington Medical Group | Everett | Washington | 98208 | — |
| Allergy Asthma and Sinus Center-Greenfield | Greenfield | Wisconsin | 53228-3467 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 329 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05595642, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2026 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05595642 live on ClinicalTrials.gov.