Alzheimer's Disease Neuroimaging Initiative 4
Public ClinicalTrials.gov record NCT05617014. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Alzheimer's Disease Neuroimaging Initiative 4 (ADNI4)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Alzheimer's Disease Neuroimaging Initiative 4 (ADNI4) is a non-randomized, longitudinal, natural history study designed to validate biomarkers, improve clinical trial design, and advance understanding of Alzheimer's disease across the full disease spectrum. Building on the success of ADNI1, ADNI-GO, ADNI2, and ADNI3, ADNI4 integrates clinical, cognitive, imaging, genetic, and fluid biomarker data to characterize disease progression and predict cognitive decline. ADNI4 includes both in-clinic and remote cohorts and a small complementary sub-cohort, Together Exploring Aging Minds (TEAM-ADNI), which evaluates community-based recruitment and longitudinal data collection approaches.
Study identification
- NCT ID
- NCT05617014
- Recruitment status
- Enrolling by invitation
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 9, 2023 (Actual)
- Primary completion
- Jul 31, 2027 (Estimated)
- Completion
- Jul 31, 2027 (Estimated)
- Last update posted
- Sep 29, 2026
2023 – 2027
United States locations
- U.S. sites
- 62
- U.S. states
- 29
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| University of California, Irvine | Irvine | California | 92697 | — |
| University of California, San Diego | La Jolla | California | 92037 | — |
| University of California, Los Angeles | Los Angeles | California | 90024 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| University of California, San Francisco | San Francisco | California | 94158 | — |
| University of California, Davis | Walnut Creek | California | 94598 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Georgetown University | Washington D.C. | District of Columbia | 200072145 | — |
| Howard University | Washington D.C. | District of Columbia | 20060 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Mayo Clinic, Jacksonville | Jacksonville | Florida | 32224 | — |
| Gonzalez MD & Aswad MD Health Services | Miami | Florida | 33135 | — |
| Wien Center | Miami Beach | Florida | 33140 | — |
| Charter Research | Orlando | Florida | 32803 | — |
| University of South Florida Health Byrd Alzheimer's Institute | Tampa | Florida | 336134808 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Memory Clinic | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| AllianceChicago | Chicago | Illinois | 60654 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas | Fairway | Kansas | 66205 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Johns Hopkins University | Baltimore | Maryland | 21224 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02115 | — |
| Boston University | Boston | Massachusetts | 02118 | — |
| The Fenway Institute - Fenway Health | Boston | Massachusetts | 02215 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 21155 | — |
| University of Michigan, Ann Arbor | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic Alzheimer's Disease Research Center | Rochester | Minnesota | 55901 | — |
| Washington University, St Louis | St Louis | Missouri | 63108 | — |
| Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas | Las Vegas | Nevada | 89101 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Dent Neurological Institute | Buffalo | New York | 142261727 | — |
| New York University Langone Medical Center | New York | New York | 10016 | — |
| Clinical Directors Network, Inc | New York | New York | 10018 | — |
| Mount Sinai School of Medicine | New York | New York | 100296552 | — |
| Columbia University Irving Medical Center | New York | New York | 10032 | — |
| Nathan Kline Institute for Psychiatric Research | Orangeburg | New York | 109621159 | — |
| University of Rochester | Rochester | New York | 14620 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Case Western Reserve University | Cleveland | Ohio | 44122 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Central States Research | Tulsa | Oklahoma | 74136 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Butler Hospital, Memory and Aging Program | Providence | Rhode Island | 02906 | — |
| Ralph H. Johnson VA Health Care System | Charleston | South Carolina | 29401 | — |
| Vanderbilt University Medical Center Center for Cognitive Medicine | Nashville | Tennessee | 37212 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05617014, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05617014 live on ClinicalTrials.gov.