A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Public ClinicalTrials.gov record NCT05617677. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Participants With Active Systemic Lupus Erythematosus (SLE) (POETYK SLE-1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population.
Study identification
- NCT ID
- NCT05617677
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 516 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 12, 2023 (Actual)
- Primary completion
- Oct 19, 2026 (Estimated)
- Completion
- Nov 13, 2028 (Estimated)
- Last update posted
- Dec 3, 2025
2023 – 2028
United States locations
- U.S. sites
- 48
- U.S. states
- 21
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0012 | Birmingham | Alabama | 35205 | — |
| Local Institution - 0229 | Phoenix | Arizona | 85006 | — |
| Local Institution - 0193 | Tucson | Arizona | 85724 | — |
| Kaiser Permanente | Fontana | California | 92335 | — |
| Local Institution - 0247 | La Mesa | California | 91942 | — |
| Local Institution - 0090 | La Palma | California | 90623 | — |
| Local Institution - 0124 | Los Angeles | California | 90095 | — |
| Local Institution - 0248 | Sacramento | California | 95817 | — |
| Local Institution - 0253 | San Diego | California | 92128 | — |
| Local Institution - 0128 | Santa Barbara | California | 93108 | — |
| Local Institution - 0099 | Denver | Colorado | 80230 | — |
| Local Institution - 0054 | New Haven | Connecticut | 06510 | — |
| Local Institution - 0249 | Coral Springs | Florida | 33065 | — |
| Local Institution - 0010 | Gainesville | Florida | 32610 | — |
| Local Institution - 0087 | Miami | Florida | 33136 | — |
| Local Institution - 0007 | Orlando | Florida | 32806 | — |
| Local Institution - 0242 | Plantation | Florida | 33317 | — |
| Local Institution - 0002 | Tamarac | Florida | 33321 | — |
| Local Institution - 0165 | Tampa | Florida | 33614 | — |
| Local Institution - 0204 | Atlanta | Georgia | 30318 | — |
| Local Institution - 0228 | Lawrenceville | Georgia | 30044 | — |
| Local Institution - 0147 | Lawrenceville | Georgia | 30046 | — |
| Local Institution - 0227 | Morton Grove | Illinois | 60053 | — |
| Local Institution - 0077 | Schaumburg | Illinois | 60195 | — |
| Local Institution - 0108 | Indianapolis | Indiana | 46202 | — |
| Lake Cumberland Rheumatology | New Albany | Indiana | 47150 | — |
| Local Institution - 0225 | New Orleans | Louisiana | 70121 | — |
| Local Institution - 0006 | Detroit | Michigan | 48202 | — |
| Local Institution - 0179 | Eagan | Minnesota | 55121 | — |
| Local Institution - 0177 | Summit | New Jersey | 07901 | — |
| Local Institution - 0180 | Manhasset | New York | 11030 | — |
| Local Institution - 0085 | New York | New York | 10016 | — |
| Local Institution - 0098 | Rochester | New York | 14642 | — |
| Local Institution - 0159 | The Bronx | New York | 10467 | — |
| Local Institution - 0245 | Charlotte | North Carolina | 28207 | — |
| Local Institution - 0155 | Charlotte | North Carolina | 28211 | — |
| Local Institution - 0246 | Summerville | South Carolina | 29486 | — |
| Local Institution - 0003 | Memphis | Tennessee | 38119 | — |
| Local Institution - 0064 | Allen | Texas | 75013 | — |
| Local Institution - 0065 | Dallas | Texas | 75390 | — |
| Local Institution - 0088 | Fort Worth | Texas | 76177 | — |
| Local Institution - 0250 | Houston | Texas | 77090 | — |
| Local Institution - 0219 | Lubbock | Texas | 79415 | — |
| Local Institution - 0005 | The Woodlands | Texas | 77382 | — |
| Local Institution - 0009 | Roanoke | Virginia | 24016 | — |
| Local Institution - 0011 | Seattle | Washington | 98122 | — |
| Local Institution - 0139 | Seattle | Washington | 98195 | — |
| Local Institution - 0063 | Franklin | Wisconsin | 53132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 149 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05617677, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 3, 2025 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05617677 live on ClinicalTrials.gov.