A Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD)
Public ClinicalTrials.gov record NCT05619692. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance in participants with Alzheimer's Disease.
Study identification
- NCT ID
- NCT05619692
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 174 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 29, 2022 (Actual)
- Primary completion
- Jun 5, 2024 (Actual)
- Completion
- Jul 9, 2024 (Actual)
- Last update posted
- Sep 15, 2025
2022 – 2024
United States locations
- U.S. sites
- 37
- U.S. states
- 19
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sage Investigational Site | Gilbert | Arizona | 85297 | — |
| Sage Investigational Site | Phoenix | Arizona | 85297 | — |
| Sage Investigational Site | Lafayette | California | 94549 | — |
| Sage Investigational Site | Long Beach | California | 90808 | — |
| Sage Investigational Site | Redlands | California | 92374 | — |
| Sage Investigational Site | San Diego | California | 92123 | — |
| Sage Investigational Site | Sherman Oaks | California | 91403 | — |
| Sage Investigational Site | Englewood | Colorado | 80120 | — |
| Sage Investigational Site | Hollywood | Florida | 33024 | — |
| Sage Investigational Site | Jacksonville | Florida | 32256 | — |
| Sage Investigational Site | Miami | Florida | 33155 | — |
| Sage Investigational Site | Palm Beach Gardens | Florida | 33410 | — |
| Sage Investigational Site | Pensacola | Florida | 32504 | — |
| Sage Investigational Site | Tampa | Florida | 33609 | — |
| Sage Investigational Site | Winter Park | Florida | 32789 | — |
| Sage Investigational Site | Decatur | Georgia | 30030 | — |
| Sage Investigational Site | Savannah | Georgia | 31404 | — |
| Sage Investigational Site | Honolulu | Hawaii | 96817 | — |
| Sage Investigational Site | Meridian | Idaho | 83642 | — |
| Sage Investigational Site | Chicago | Illinois | 60640 | — |
| Sage Investigational Site | Charlestown | Massachusetts | 02129 | — |
| Sage Investigational Site | Methuen | Massachusetts | 01844 | — |
| Sage Investigational Site | Chesterfield | Missouri | 63005 | — |
| Sage Investigational Site | Papillion | Nebraska | 68046 | — |
| Sage Investigational Site | Toms River | New Jersey | 08755 | — |
| Sage Investigational Site | Albuquerque | New Mexico | 87109 | — |
| Sage Investigational Site | Brooklyn | New York | 11229 | — |
| Sage Investigational Site | Buffalo | New York | 14203 | — |
| Sage Investigational Site | Staten Island | New York | 10312 | — |
| Sage Investigational Site | Raleigh | North Carolina | 27607 | — |
| Sage Investigational Site | Abington | Pennsylvania | 19001 | — |
| Sage Investigational Site | Memphis | Tennessee | 38119 | — |
| Sage Investigational Site | Nashville | Tennessee | 37212 | — |
| Sage Investigational Site | Austin | Texas | 78731 | — |
| Sage Investigational Site | Dallas | Texas | 75231 | — |
| Sage Investigational Site | Houston | Texas | 77030 | — |
| Sage Investigational Site | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05619692, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 15, 2025 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05619692 live on ClinicalTrials.gov.