Multisite Advancement of Research on Chronic Posttraumatic Headache
Public ClinicalTrials.gov record NCT05620719. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Project MARCH: Multisite Advancement of Research on Chronic Posttraumatic Headache
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Posttraumatic headache (PTH) is a common and highly disabling consequence of traumatic brain injury (TBI) in U.S. military service members and veterans. Cognitive Behavioral Therapy for PTH has been shown to significantly improve disability outcomes in veterans with persistent PTH when delivered in-person. Telemedicine platforms can dramatically increase access to evidence-based care. However, whether CBT for PTH retains its effectiveness when delivered through a telemedicine platform has yet to be established. The purpose of this 3-arm randomized clinical trial is to compare Clinic-based Cognitive-Behavioral Therapy (CCBT) to Telemedicine-based Cognitive Behavioral Therapy (TCBT) and to treatment as usual (TAU) in 525 service members and veterans with chronic posttraumatic headaches (PTH) at 4 VA medical centers\* and 3 military treatment facilities across the U.S. Participants will be assessed for headache-related disability, headache experience, and psychiatric comorbidities across multiple time points. \*VA Palo Alto Health Care System is temporarily randomizing into TAU and TCBT only.
Study identification
- NCT ID
- NCT05620719
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 525 participants
Conditions and interventions
Conditions
Interventions
- Cognitive Behavioral Therapy for Posttraumatic Headache Behavioral
- Treatment as Usual Other
- Telemedicine-based Cognitive Behavioral Therapy (TCBT) Other
Behavioral · Other
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2023 (Actual)
- Primary completion
- Sep 2026 (Estimated)
- Completion
- Aug 2027 (Estimated)
- Last update posted
- Sep 22, 2026
2023 – 2027
United States locations
- U.S. sites
- 8
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | Recruiting |
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | Recruiting |
| Tripler Army Medical Center (Desmond Doss Health Clinic, Schofield Barracks) | Honolulu | Hawaii | 96819 | Completed |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | Withdrawn |
| Minneapolis VA Health Care System | Minneapolis | Minnesota | 55417 | Active, not recruiting |
| Carl R. Darnall Army Medical Center (Fort Cavazos) | Killeen | Texas | 76544 | Recruiting |
| South Texas Veterans Health Care System | San Antonio | Texas | 78229 | Recruiting |
| Brooke Army Medical Center | San Antonio | Texas | 78234 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05620719, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 22, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05620719 live on ClinicalTrials.gov.